ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Pyridine derivatives >Methyl 5-bromo-2-chloropyridine-3-carboxylate
Methyl 5-bromo-2-chloropyridine-3-carboxylate
- CAS No.
- 78686-79-0
- Chemical Name:
- Methyl 5-bromo-2-chloropyridine-3-carboxylate
- Synonyms
- METHYL 5-BROMO-2-CHLORONICOTINATE;methyl 2-chloro-5-bromonicotinate;Methyl5-Bromo-2-chloronicotinate>Methyl 5-bromo-2-chloronicotinate 98%;Methyl 5-broMo-2-chloronicotinate, 95+%;2-Chloro-5-bromonicotinic acid methyl ester;5-BROMO-2-CHLORONICOTINIC ACID METHYL ESTER;Methyl 5-bromo-2-chloropyridine-3-carboxlate;methyl 5-bromo-2-chloro-3-pyridinecarboxylate;METHYL 5-BROMO-2-CHLOROPYRIDINE-3-CARBOXYLATE
- CBNumber:
- CB2150790
- Molecular Formula:
- C7H5BrClNO2
- Molecular Weight:
- 250.48
- MOL File:
- 78686-79-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 50-52°C |
|---|---|
| Boiling point | 275.6±35.0 °C(Predicted) |
| Density | 1.684±0.06 g/cm3(Predicted) |
| Flash point | >110 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| pka | -3.78±0.10(Predicted) |
| form | Solid |
| color | White to Light yellow to Light orange |
| Sensitive | Light, Air & Moisture Sensitive |
| InChIKey | MOMQDEDQGJAKII-UHFFFAOYSA-N |
| CAS DataBase Reference | 78686-79-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312a-P330-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
Methyl 5-bromo-2-chloropyridine-3-carboxylate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 764477 | Methyl 5-bromo-2-chloropyridine-3-carboxylate 97% | 78686-79-0 | 1G | ₹4925.38 | 2022-06-14 | Buy |
| ALFA India | ALF-H64791-22 | Methyl 5-bromo-2-chloronicotinate, 98% | 78686-79-0 | 100g | ₹72257 | 2022-05-26 | Buy |
| ALFA India | ALF-H64791-14 | Methyl 5-bromo-2-chloronicotinate, 98% | 78686-79-0 | 25g | ₹24299 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2513 | Methyl 5-Bromo-2-chloronicotinate min. 98.0 % | 78686-79-0 | 5G | ₹2200 | 2022-05-26 | Buy |
| ALFA India | ALF-H64791-06 | Methyl 5-bromo-2-chloronicotinate, 98% | 78686-79-0 | 5g | ₹2329 | 2022-05-26 | Buy |
Methyl 5-bromo-2-chloropyridine-3-carboxylate Chemical Properties,Uses,Production
Synthesis
Methyl 5-bromo-2-chloropyridine-3-carboxylate is prepared by the reaction of 5-Bromo-2-chloronicotinic acid and Methanol. The specific synthesis steps are as follows:
To 0.5 L flask charged with 5-Bromo-2-chloronicotinic acid (25.0 g, 106.4 mmol) in MeOH (250 mL) was added H2SO4(5 mL). The mixture was heated to 60° C., stirred for 1.5 day. LC-MS indicated full conversion of starting material at this time. The reaction was cooled to RT and the volatile components removed in vacuo. The crude residue was dissolved in EtOAc (300 mL), quenched with sat. aqueous Na(HCO3)2(200 mL). The organic layer was separated, washed with brine, dried over MgSO4and concentrated to afford the compound, methyl-5-bromo-2-chloronicotinate, as a while solid (quantitative yield). LC-MS (M+H)=250.1.
Methyl 5-bromo-2-chloropyridine-3-carboxylate Preparation Products And Raw materials
Global( 219)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Ms Life Sciences | 08048372386Ext 826 | Hyderabad, India | 341 | 58 | Inquiry |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | China | 2472 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29730 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19825 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
78686-79-0(Methyl 5-bromo-2-chloropyridine-3-carboxylate)Related Search:
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METHYL 5-BROMO-2-CHLOROPYRIDINE-3-CARBOXYLATE
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METHYL 5-BROMO-2-CHLORONICOTINATE
78686-79-0
C7H5BrClNO2
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