tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate

tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate Structure
CAS No.
375846-25-6
Chemical Name:
tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate
Synonyms
Fluvastatin Alcohol Ketone;CHEYRYWZYKYUHU-CCEZHUSRSA-N;tert-Butyl (E)-7-[3'-(4''...;t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-y...;t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6;t-Butyl(E)-7-[3-(4-fluorophenyl)-1-methylethyl-indol-yl]-3hydroxy-5-oxo-6-heptenoate;T-BUTYL(E)-7-[3'-(4''-FLUOROPHENYL)-1'METHYLETHYL-INDOL-2'YL]-3HYDROXY-5-OXO-6-HEPTENOATE;t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoat;T-butyl(E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxohept-6-enoate;t-Butyl(E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate
CBNumber:
CB2159854
Molecular Formula:
C28H32FNO4
Molecular Weight:
465.56
MOL File:
375846-25-6.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:54

tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate Properties

Boiling point 647.7±55.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
pka 10.35±0.46(Predicted)
form Solid
color Light Yellow to Yellow
Stability Hygroscopic

tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate Chemical Properties,Uses,Production

Uses

(6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of metabolite of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor used as an antilipemic agent.

tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl (e)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate T-BUTYL(E)-7-[3'-(4''-FLUOROPHENYL)-1'METHYLETHYL-INDOL-2'YL]-3HYDROXY-5-OXO-6-HEPTENOATE t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6 T-butyl(E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxohept-6-enoate (+)-(E)-7-(3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL) INDOL-2-YL)-5-HYDROXY-3-OXOHEPT-6-ENOI TERT BUTYL ESTER tert-Butyl (E)-7-[3'-(4''... ert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-Methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate t-Butyl(E)-7-[3-(4-fluorophenyl)-1-methylethyl-indol-yl]-3hydroxy-5-oxo-6-heptenoate TIANFUCHEM--375846-25-6--High purity tert-Butyl (E)-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate factory price t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-y... (+) -E-7-(3-(4-FLUOROPHENYL)-1-(1- METHYLETHYL)INDOL-2-YL)-5- HYDROXY-3- OXOHEPT-6ENOIC ACID TERT BUTYL ESTER 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (6E)- t-Butyl(E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate 7-[3-(4-fluorophenyl)-1-propan-2-yl-2-indolyl]-3-hydroxy-5-oxo-6-heptenoic acid tert-butyl ester CHEYRYWZYKYUHU-CCEZHUSRSA-N Fluvastatin Alcohol Ketone 2-Methyl-2-propanyl (6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate t-Butyl(E)-7-[3'-(4''-fluorophenyl)-1'methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoat 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol2-yl]-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (6E)- (9CI, ACI) 375846-25-6