Alizapride

Alizapride Structure
CAS No.
59338-93-1
Chemical Name:
Alizapride
Synonyms
MS-5080;Litican;Plitican;Nausilen;Vergentan;ALIZAPRIDE;Alizapride CAS NO.59338-93-1;VergentanQ: What is Vergentan Q: What is the CAS Number of Vergentan;n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide;N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-2H-benzotriazole-5-carboxamide
CBNumber:
CB2162373
Molecular Formula:
C16H21N5O2
Molecular Weight:
315.37
MOL File:
59338-93-1.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

Alizapride Properties

Melting point 139°
Boiling point 580.3±40.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 7.09±0.40(Predicted)
CAS DataBase Reference 59338-93-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P280
Toxicity LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau)

Alizapride Chemical Properties,Uses,Production

Originator

Plitican ,Delagrange ,France ,1981

Manufacturing Process

38.6 g (0.2 mol) of 2-methoxy-4,5-azimidobenzoic acid were dissolved in anhydrous toluene and 56 g (0.4 mol) of 1-allyl-2-amino-methylpyrrolidine were added. The mixture was heated to 50°C and then 42 g (0.3 mol) of phosphoric anhydride were added. The mixture was warmed at reflux temperature for 3 hours and then cooled to 80°C. After adding water, the aqueous layer was alkalized. The crystals were filtered, washed with water and then dissolved in 450 ml of acetone. After crystallization, the product was 40.4 g (yield 65%) of N-(1'-allyl-2'-pyrrolidylmethyl)-2-methoxy-4,5- azimidobenzamide having a melting point of 139°C were obtained.

Therapeutic Function

Neuroleptic, Antiemetic

Global( 45)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Viyash Life Sciences Pvt Ltd +91-4023635052 +91-4023635052 Telangana, India 213 58 Inquiry
Symed Laboratories Ltd +91-9505426644 +91-9505426644 Telangana, India 54 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 992 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
ALIZAPRIDE n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide 1h-benzotriazole-5-carboxamide,6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)met 6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)methyl)-1h-benzotriazole-5-carbo Nausilen Plitican Vergentan 6-Methoxy-N-{[1-(2-propnyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Litican 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide MS-5080 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-2H-benzotriazole-5-carboxamide 1H-Benzotriazole-5-carboxaMide,6-Methoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]Methyl]- N-((1-Allylpyrrolidin-2-yl)Methyl)-6-Methoxy-1H-benzo[d][1,2,3]triazole-5-carboxaMide VergentanQ: What is Vergentan Q: What is the CAS Number of Vergentan Alizapride CAS NO.59338-93-1 59338-93-1 89338-87-3 C16H21N5O2