D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- CAS No.
- 103404-90-6
- Chemical Name:
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- Synonyms
- d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
- CBNumber:
- CB2266017
- Molecular Formula:
- C5H9NaO5
- Molecular Weight:
- 172.11
- MOL File:
- 103404-90-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:03
Melting point | >291°C (dec.) |
---|---|
storage temp. | -20°C |
solubility | PBS (pH 7.2): 10 mg/ml |
form | A crystalline solid |
color | White to light yellow |
optical activity | [α]/D 8.5±1.5°, c = 1 in NaOH |
Water Solubility | Soluble to 100 mM in water |
BRN | 5318041 |
Stability | Hygroscopic |
InChIKey | DZHFTEDSQFPDPP-HWYNEVGZSA-L |
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H8378 | D-α-Hydroxyglutaric acid disodium salt ≥95% (GC) | 103404-90-6 | 100MG | ₹31295.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H8378 | D-α-Hydroxyglutaric acid disodium salt ≥95% (GC) | 103404-90-6 | 250MG | ₹52815.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 16859 | D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) | 103404-90-6 | 10MG | ₹5098.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 16859 | D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) | 103404-90-6 | 50MG | ₹20361.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 16859 | D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) | 103404-90-6 | 250MG | ₹62720.05 | 2022-06-14 | Buy |
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemical Properties,Uses,Production
Description
D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.
Chemical Properties
Pale Orange Solid
Uses
A potential inhibitor of glutamate carboxypeptidase.
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13341 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24099 | 58 | Inquiry |
Supplier | Advantage |
---|---|
A.J Chemicals | 58 |
CHEMSWORTH | 30 |
CLEARSYNTH LABS LTD. | 58 |
ATK CHEMICAL COMPANY LIMITED | 60 |
career henan chemical co | 58 |
BOC Sciences | 58 |
Chongqing Chemdad Co., Ltd | 58 |
CONIER CHEM AND PHARMA LIMITED | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | 58 |
Dideu Industries Group Limited | 58 |