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indoleaMine-2,3-dioxygenase inhibitor INCB024360

indoleaMine-2,3-dioxygenase inhibitor INCB024360 Structure
CAS No.
914471-09-3
Chemical Name:
indoleaMine-2,3-dioxygenase inhibitor INCB024360
Synonyms
IDO5L;CS-1034;IDO-IN-2;INCB14943;INCB024360;INCB-24360;INCB 024360;INCB-024360;IDO inhibitor;4-diaminobutane
CBNumber:
CB22666639
Molecular Formula:
C9H7ClFN5O2
Molecular Weight:
271.64
MOL File:
914471-09-3.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03

indoleaMine-2,3-dioxygenase inhibitor INCB024360 Properties

Boiling point 504.7±60.0 °C(Predicted)
Density 1.78±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥13.55 mg/mL in DMSO
pka 7.54±0.69(Predicted)
form Solid
color Off-white to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

indoleaMine-2,3-dioxygenase inhibitor INCB024360 Chemical Properties,Uses,Production

Uses

INCB024360 acts as a competitive inhibitor of (IDO1) indoleamine 2,3-dioxygenase showing effect in mouse melanoma models. IC50 = 67 nM

indoleaMine-2,3-dioxygenase inhibitor INCB024360 Preparation Products And Raw materials

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indoleaMine-2,3-dioxygenase inhibitor INCB024360 Spectrum

CS-1034 Epacadostat-analog INCB14943 INCB024360 analogue(IDO-IN-1) 3-dioxygenase inhibitor INCB024360 INCB-024360; INCB 024360; INCB-24360; INDOLEAMINE-2;3-DIOXYGENASE INHIBITOR INCB024360 indoleaMine-2,3-dioxygenase inhibitor INCB 024360-analog - IDO inhibitor 5l (4E)-4-[(3-chloro-4-fluoroanilino)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine INCB 024360 INCB024360 INCB-024360 INCB-24360 indoleaMine-2,3-dioxygenase inhibitor INCB024360 INCB024360/INCB-024360 4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide INCB024360 IDO-IN-2 INCB024360 analogue (E)-4-Amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide IDO5L INCB024360 analog IDO inhibitor INCB024360 ANALOGUE;IDO5L INCB024360 500MG IDO-IN-2(1g 2000) INCB024360-analog(IDO-IN-2) 1,2,5-Oxadiazole-3-carboximidamide, 4-amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy- indoleaMine-2,3-dioxygenase inhibitor INCB024360 USP/EP/BP 4-diaminobutane N-(3-Aminopropyl)-1 N-(4-Aminobutyl)-1 4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboxamidine 4-Amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide 914471-09-3 C9H7ClFN5O2 Inhibitors