L-Ser-OBzl.HCl
- CAS No.
- 60022-62-0
- Chemical Name:
- L-Ser-OBzl.HCl
- Synonyms
- H-SER-OBZL·HCL;H-SER-OBZL HCL;SERINE-OBZL HCL;H-L-Ser-OBzl.HCl;L-SerinebenzylesterHCl;H-L-Ser-Obzl*Hydrochloride;L-SERINE BENZYL ESTER HYDROCHLORIDE;L-SerineBenzylEsterHydrochloride>Benzyl serinate hydrochloride (1:1);benzyl (2S)-2-amino-3-hydroxypropanoate
- CBNumber:
- CB2286886
- Molecular Formula:
- C10H14ClNO3
- Molecular Weight:
- 231.68
- MOL File:
- 60022-62-0.mol
- Modify Date:
- 2024/4/23 19:22:53
| Melting point | 175°C |
|---|---|
| refractive index | -12 ° (C=1, H2O) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Soluble in water. |
| InChI | InChI=1/C10H13NO3.ClH/c11-9(6-12)10(13)14-7-8-4-2-1-3-5-8;/h1-5,9,12H,6-7,11H2;1H/t9-;/s3 |
| InChIKey | MGZWCDQAKCHOBX-FVGYRXGTSA-N |
| SMILES | C(OCC1=CC=CC=C1)(=O)[C@H](CO)N.[H]Cl |&1:10,r| |
| CAS DataBase Reference | 60022-62-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WGK Germany | 3 | |||||||||
| HS Code | 29225090 | |||||||||
| NFPA 704 |
|
L-Ser-OBzl.HCl price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S5633 | L-Serine benzyl ester hydrochloride | 60022-62-0 | 5G | ₹10576.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5633 | L-Serine benzyl ester hydrochloride | 60022-62-0 | 25G | ₹35982.3 | 2022-06-14 | Buy |
| TCI Chemicals (India) | S0550 | L-Serine Benzyl Ester Hydrochloride | 60022-62-0 | 5G | ₹6000 | 2022-05-26 | Buy |
L-Ser-OBzl.HCl Chemical Properties,Uses,Production
Description
L-Serine benzyl ester hydrochloride, also known as L-Serine-Bz-HCl, is a derivative of the amino acid L-Serine. It is a water-soluble, white crystalline powder and is commonly used as a reagent in biochemical and physiological studies. It is a useful raw material that could synthesize mang organic compounds, such as a cyclic sulfamidate which could reacted cleanly with the sodium thiolate
salt of a variety of unprotected 1-thio sugars in aqueous buffer to afford the corresponding S-linked amino acid glycoconjugates in good
yields after hydrolysis of the N-sulfates[1].
Chemical Properties
Colorless solid
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Preparation
Boc-L-Ser-OBz (2.953 g, 10 mmol) was dissolved in MeOH (21 mL) and was palced in ice bath. Then concentrated hydrochloric acid (4.25 mL) was added dropwise. The ice bath was removed and the reaction mixture was stirred for 3 hours. After that the isopropanol (10 mL) was added and the volatile components were removed under reduced pressure at 55 ℃. The oily residue was coevaporated with isopropanol three times (3x10 mL). L-Serine benzyl ester hydrochloride ( yield=69%) was crystallized from H2O/iPr-OH/acetone mixture.
References
[1] Cohen S, et al. Synthesis of S-linked glycosyl amino acids in aqueous solution with unprotected carbohydrates. Organic Letters, 2001; 3: 405–407.
L-Ser-OBzl.HCl Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | China | 1106 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20290 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18623 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32835 | 60 | Inquiry |