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Glucagon Receptor Antagonist I

Glucagon Receptor Antagonist I Structure
CAS No.
438618-32-7
Chemical Name:
Glucagon Receptor Antagonist I
Synonyms
hGCGR Antagonist;Glucagon Receptor Antagonist I;Butanamide, N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-;N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide
CBNumber:
CB23136786
Molecular Formula:
C20H30N2OS
Molecular Weight:
346.53
MOL File:
438618-32-7.mol
Modify Date:
2023/5/21 10:59:17
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Glucagon Receptor Antagonist I Properties

Boiling point 517.8±50.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: soluble
form White crystalline solid.
pka 13.46±0.40(Predicted)

Glucagon Receptor Antagonist I Chemical Properties,Uses,Production

Description

Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.

Glucagon Receptor Antagonist I Preparation Products And Raw materials

Raw materials

Preparation Products

Glucagon Receptor Antagonist I Suppliers

Global( 13)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
EvoBlocks, Ltd. +36 (20) 5757-305 Hungary 5008 50 Inquiry
Manchester Organics +44 1928 710 200 United Kingdom 6844 67 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4398 58 Inquiry
Supplier Advantage
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
EvoBlocks, Ltd. 50
Manchester Organics 67
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
Nantong QuanYi Biotechnology Co., Ltd 58

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Glucagon Receptor Antagonist I N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide Butanamide, N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl- hGCGR Antagonist 438618-32-7