SUCCINYL COENZYME A SODIUM SALT
- CAS No.
- 108347-97-3
- Chemical Name:
- SUCCINYL COENZYME A SODIUM SALT
- Synonyms
- Succinyl CoA, Li-salt;succinyl coenzyme A sodium;SUCCINYL COENZYME A SODIUM SALT;Succinyl coenzyme A sodium salt >=85%;coenzyme A succinyl derivative, trisodium salt;Coenzyme A,S-(hydrogen butanedioate),sodium salt;Coenzyme A, S-(hydrogenbutanedioate), sodium salt (9CI)
- CBNumber:
- CB2444570
- Molecular Formula:
- C25H41N7NaO19P3S
- Molecular Weight:
- 891.6
- MOL File:
- 108347-97-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:03
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
SUCCINYL COENZYME A SODIUM SALT price More Price(2)
SUCCINYL COENZYME A SODIUM SALT Chemical Properties,Uses,Production
Description
Succinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle. It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis. Succinyl-CoA deficiency, caused by vitamin B12 deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.
Uses
Succinyl coenzyme A sodium salt has been used:
- for the nonenzymatic succinylation of lysine in vitro,
- as a substrate for adipic acid biosynthesis in recombinant E. coli
- in isocitrate dehydrogenase (ICDH)?treatment for the succinylation of proteins
- as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)
Purification Methods
If it should be purified further, then it should be dissolved in H2O (0.05g/mL) adjusted to pH 1 with 2M H2SO4 and extracted several times with Et2O. Excess Et2O is removed from the aqueous layer by bubbling N2 through it and is stored frozen at pH 1. When required, the pH should be adjusted to 7 with dilute NaOH and used within 2 weeks (samples should be frozen). Succinyl coenzyme A is estimated by the hydroxamic acid method [Hersch & Jencks J Biol Chem 242 3468 1967]. It is more stable in acidic than in neutral aqueous solutions, but neutral solutions can be stored at –15o with negligible decomposition. [Jordan & Laghai-Newton Methods Enzymol 123 435 1986, Beilstein 26 III/IV 3666.]
SUCCINYL COENZYME A SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
SUCCINYL COENZYME A SODIUM SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | China | 10678 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 28118 | 58 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 19921389125 19921389125 | China | 12065 | 58 | Inquiry |
| Shanghai klamar Reagent Co., LTD | 4001650900 13817534909 | China | 10709 | 58 | Inquiry |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815987 13927875076 | China | 9977 | 58 | Inquiry |
| Guangzhou Yunmen Biotechnology Co., Ltd | 18902340307 18902340307 | China | 9241 | 58 | Inquiry |
| cjbscvictory | 13348960310 13348960310 | China | 10011 | 58 | Inquiry |