Remoxipride
- CAS No.
- 80125-14-0
- Chemical Name:
- Remoxipride
- Synonyms
- Roxiam;FLA-731;A-33547;REMOXIPRIDE;(S)-Remoxipride;Remoxipride [USAN:BAN:INN];(S)-3-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2，6-dimethoxybenzamide;(S)-3-BroMo-N-((1-ethylpyrrolidin-2-yl)Methyl)-2,6-diMethoxybenzaMide;3-Bromo-2,6-dimethoxy-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]benzamide;3-Bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide
- CBNumber:
- CB2493967
- Molecular Formula:
- C16H23BrN2O3
- Molecular Weight:
- 371.27
- MOL File:
- 80125-14-0.mol
- Modify Date:
- 2025/4/17 18:22:24
| alpha | D20 -64° (c = 2 in ethanol) |
|---|---|
| Boiling point | 439.9±45.0 °C(Predicted) |
| Density | 1.292 |
| storage temp. | 2-8°C |
| pka | pKa 8.9 (Uncertain) |
| CAS DataBase Reference | 80125-14-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Remoxipride(80125-14-0) |
Remoxipride Chemical Properties,Uses,Production
Uses
Antipsychotic.
General Description
Remoxipride is a D2 receptorblocker.It is as effective as haloperidol with fewer EPS andautonomic side effects. Negative symptoms of schizophreniaare diminished. The drug is classed as an atypical antipsychotic.Life-threatening aplastic anemia was reported with itsuse, which prompted its withdrawal from the market.
With respect to the atypical antipsychotics, two eventslong in the past may shed some light on the events of today.
The field of reuptake-inhibiting antidepressants arose whenonly a very small structural change was made in an antipsychoticdrug, and the new activity noted. (The antipsychoticactivity remained.) Therefore, small changes in structurecan produce antipsychotics that are active against depressivesymptoms. Likewise, small changes in structure could provideselectivity among D2 receptors.
Remoxipride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | China | 52849 | 58 | Inquiry |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | China | 6000 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +8613564774135 | United States | 19881 | 58 | Inquiry |
| Aikon International Limited | 025-58851090 15955137747 | China | 15951 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24642 | 58 | Inquiry |
| Nantong Chem-Tech.(Group) Co., Ltd | 0086-513-85081108 85335860 | Europe | 1811 | 56 | Inquiry |
| ChemPacific Corporation | 410 633 5771 | United States | 6891 | 51 | Inquiry |
| BOSCHE SCIENTIFIC, LLC | 732 565 9988 | United States | 6477 | 55 | Inquiry |
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