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CYCLIC-PIFITHRIN-ALPHA

CYCLIC-PIFITHRIN-ALPHA Structure
CAS No.
60477-34-1
Chemical Name:
CYCLIC-PIFITHRIN-ALPHA
Synonyms
Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
CBNumber:
CB2504209
Molecular Formula:
C16H16N2S
Molecular Weight:
268.38
MOL File:
60477-34-1.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:07
Request For Quotation

CYCLIC-PIFITHRIN-ALPHA Properties

Melting point 266.4-267.3 °C(lit.)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: 20 mg/mL
form White solid
pka 6.75±0.20(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

CYCLIC-PIFITHRIN-ALPHA Chemical Properties,Uses,Production

General Description

A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.

Biochem/physiol Actions

Cell permeable: yes

CYCLIC-PIFITHRIN-ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLIC-PIFITHRIN-ALPHA Suppliers

Global( 28)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
InvivoChem 13549236410 China 6749 58 Inquiry
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 China 10015 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
InvivoChem 58
Amadis Chemical Company Limited 58
DC Chemicals 58
InvivoChem 58
Henan Alpha Chemical Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
ApexBio Technology 58

60477-34-1(CYCLIC-PIFITHRIN-ALPHA)Related Search:

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Pifithrin-alpha (cyclic) . HBr 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem Pifithrin-2 Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)- Pifithrin-β (QB-102 and Cyclic-Pifithrin-α) 2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 60477-34-1