JX401

JX401 Structure
CAS No.
349087-34-9
Chemical Name:
JX401
Synonyms
JX401;p38 MAP Kinase Inhibitor VI, JX401;1-[2-Methoxy-4-(methylthio)benzoyl]-4-benzylpiperidine;1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine;p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9 - Calbiochem;Methanone, [2-methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]-
CBNumber:
CB01074327
Molecular Formula:
C21H25NO2S
Molecular Weight:
355.49
MOL File:
349087-34-9.mol
Modify Date:
2023/6/30 15:45:59

JX401 Properties

storage temp. Store at RT
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form Off-white solid
color White
Stability Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P391-P501
Hazard Codes  N
Risk Statements  50/53
Safety Statements  60-61
RIDADR  UN 3077 9/PG 3

JX401 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 506157 p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9 - Calbiochem The p38 MAP Kinase Inhibitor VI, JX401, also referenced under CAS 349087-34-9, controls the biological activity of p38 MAP Kinase. This small molecule 349087-34-9 5MG ₹16670.01 2022-06-14 Buy
Product number Packaging Price Buy
506157 5MG ₹16670.01 Buy

JX401 Chemical Properties,Uses,Production

Uses

JX-401 is a potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM). It does not inhibit the p38γ isoform. JX-401 is effective in mammalian cells, as it blocks the differentiation of myoblasts into myotubes.[Cayman Chemical]

Biological Activity

Potent, reversible inhibitor of p38 α that displays no activity on the p38 γ isoform (IC 50 values are 32 nM and > 10 μ M respectively). Inhibits the differentiation of myoblasts to myotubes in mammalian cells in culture.

JX401 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 60)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Jinan Jiuli Biotechnology Co. , Ltd. 14768611851 China 2041 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4455 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
JX401 1-[2-Methoxy-4-(methylthio)benzoyl]-4-benzylpiperidine 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine p38 MAP Kinase Inhibitor VI, JX401 p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9 - Calbiochem Methanone, [2-methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]- 349087-34-9 Intracellular Signaling