ChemicalBook > Product Catalog >API >Circulatory system drugs >Heart failure Treatments and drugs >Enoximone
Enoximone
- CAS No.
- 77671-31-9
- Chemical Name:
- Enoximone
- Synonyms
- Perfan;Pedane;RMI-17043;ENOXIMONE;MDL-17043;Fenoximone;Enoximone USP/EP/BP;4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one;1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE;4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
- CBNumber:
- CB2682723
- Molecular Formula:
- C12H12N2O2S
- Molecular Weight:
- 248.3
- MOL File:
- 77671-31-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 255-258°C |
|---|---|
| Density | 1.33 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: 28 mg/mL, soluble |
| pka | 10.37±0.70(Predicted) |
| form | solid |
| color | light yellow |
| CAS DataBase Reference | 77671-31-9(CAS DataBase Reference) |
Enoximone Chemical Properties,Uses,Production
Description
Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.
Uses
Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.
Biological Activity
Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .
Enoximone Preparation Products And Raw materials
Global( 95)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32835 | 60 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49403 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 7726 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | China | 6950 | 58 | Inquiry |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Shanghai Chaoyan Biotechnology Co., Ltd. | 021-50840550 | CHINA | 6217 | 58 | Inquiry |
| Shanghai Hao Biological Technology Co., Ltd. | 021-58116080 18019263206 | CHINA | 6921 | 58 | Inquiry |
77671-31-9(Enoximone)Related Search:
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ENOXIMONE
2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
Fenoximone
MDL-17043
Pedane
Perfan
RMI-17043
4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE
4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one
Enoximone USP/EP/BP
4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one
inhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),airway,cAMP,PDE3,PDE4A,Inhibitor,anti-inflammatory,Antiasthma
77671-31-9
BioChemical
Cell Signaling and Neuroscience
G Proteins and Cyclic Nucleotides
Phosphodiesterase Inhibitors
Cyclic Nucleotide Metabolism
Cell Biology
APIs
API