Rhodamine 123

- CAS No.
- 62669-70-9
- Chemical Name:
- Rhodamine 123
- Synonyms
- rh123;R 302;R 22420;RHODAMINE 123;-Cellstain-Rh123;Rhodamine 123 ,98%;Rhodamine 123, 99+%;Rhodamine 123, pure;Rhodamine 123 (RH-123;Rhodamine 123 Chloride
- CBNumber:
- CB2702364
- Molecular Formula:
- C21H17ClN2O3
- Molecular Weight:
- 380.83
- MOL File:
- 62669-70-9.mol
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 235 °C |
---|---|
Density | 1.2224 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | ethanol: 20 mg/mL, clear, red |
form | Powder |
color | Red-brown to brown or dark green |
Water Solubility | Partially soluble |
λmax | 501 nm, 507 nm |
BRN | 6030951 |
Stability | Hygroscopic |
Biological Applications | Measuring membrane potential; detecting cancer cells,spores,prostate cancer,stress biomarkers; treating disc degenerative disease,epilepsy,erectile dysfunction; apoptosis assays; tumor cell multidrug resistance assay; implantable |
Major Application | Colored bubbles; color filters; liquid crystal displays; light-emitting diodes; luminescent materials;nanophotonic composites; paints; semiconductor electrodes;solar cells |
InChIKey | MYFATKRONKHHQL-UHFFFAOYSA-N |
CAS DataBase Reference | 62669-70-9(CAS DataBase Reference) |
EPA Substance Registry System | Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (62669-70-9) |
Rhodamine 123 price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | R8004 | Rhodamine 123 mitochondrial specific fluorescent dye | 62669-70-9 | 5MG | ₹3840.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R8004 | Rhodamine 123 mitochondrial specific fluorescent dye | 62669-70-9 | 25MG | ₹12765 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R8004 | Rhodamine 123 mitochondrial specific fluorescent dye | 62669-70-9 | 100MG | ₹41314.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 83702 | Rhodamine 123 BioReagent, for fluorescence, ≥85% (HPLC) | 62669-70-9 | 10MG | ₹5250.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 83702 | Rhodamine 123 BioReagent, for fluorescence, ≥85% (HPLC) | 62669-70-9 | 50MG | ₹19558.2 | 2022-06-14 | Buy |
Rhodamine 123 Chemical Properties,Uses,Production
Description
Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp; also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem cells known as the side population, rhodamine 123 is used to detect this group of stem cells. Rhodamine 123 also accumulates within mitochondria due to its positive charge and can inhibit oxidative phosphorylation. Rhodamine 123 has excitation/emission maxima of 507/529 nm.
Chemical Properties
red-brown to brown or dark green powder
Uses
Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).
Rhodamine 123 Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3882 | 58 | Inquiry |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12809 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | China | 19808 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29859 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | China | 3256 | 58 | Inquiry |