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Rhodamine 123

Rhodamine 123 Structure
CAS No.
62669-70-9
Chemical Name:
Rhodamine 123
Synonyms
rh123;R 302;R 22420;RHODAMINE 123;-Cellstain-Rh123;Rhodamine 123 ,98%;Rhodamine 123, 99+%;Rhodamine 123, pure;Rhodamine 123 (RH-123;Rhodamine 123 Chloride
CBNumber:
CB2702364
Molecular Formula:
C21H17ClN2O3
Molecular Weight:
380.83
MOL File:
62669-70-9.mol
Modify Date:
2025/1/27 9:38:02

Rhodamine 123 Properties

Melting point 235 °C
Density 1.2224 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility ethanol: 20 mg/mL, clear, red
form Powder
color Red-brown to brown or dark green
Water Solubility Partially soluble
λmax 501 nm, 507 nm
BRN 6030951
Stability Hygroscopic
Biological Applications Measuring membrane potential; detecting cancer cells,spores,prostate cancer,stress biomarkers; treating disc degenerative disease,epilepsy,erectile dysfunction; apoptosis assays; tumor cell multidrug resistance assay; implantable
Major Application Colored bubbles; color filters; liquid crystal displays; light-emitting diodes; luminescent materials;nanophotonic composites; paints; semiconductor electrodes;solar cells
InChIKey MYFATKRONKHHQL-UHFFFAOYSA-N
CAS DataBase Reference 62669-70-9(CAS DataBase Reference)
EPA Substance Registry System Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (62669-70-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  ZE0883000
HS Code  32049010
NFPA 704
0
2 0

Rhodamine 123 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) R8004 Rhodamine 123 mitochondrial specific fluorescent dye 62669-70-9 5MG ₹3840.6 2022-06-14 Buy
Sigma-Aldrich(India) R8004 Rhodamine 123 mitochondrial specific fluorescent dye 62669-70-9 25MG ₹12765 2022-06-14 Buy
Sigma-Aldrich(India) R8004 Rhodamine 123 mitochondrial specific fluorescent dye 62669-70-9 100MG ₹41314.2 2022-06-14 Buy
Sigma-Aldrich(India) 83702 Rhodamine 123 BioReagent, for fluorescence, ≥85% (HPLC) 62669-70-9 10MG ₹5250.3 2022-06-14 Buy
Sigma-Aldrich(India) 83702 Rhodamine 123 BioReagent, for fluorescence, ≥85% (HPLC) 62669-70-9 50MG ₹19558.2 2022-06-14 Buy
Product number Packaging Price Buy
R8004 5MG ₹3840.6 Buy
R8004 25MG ₹12765 Buy
R8004 100MG ₹41314.2 Buy
83702 10MG ₹5250.3 Buy
83702 50MG ₹19558.2 Buy

Rhodamine 123 Chemical Properties,Uses,Production

Description

Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp; also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem cells known as the side population, rhodamine 123 is used to detect this group of stem cells. Rhodamine 123 also accumulates within mitochondria due to its positive charge and can inhibit oxidative phosphorylation. Rhodamine 123 has excitation/emission maxima of 507/529 nm.

Chemical Properties

red-brown to brown or dark green powder

Uses

Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).

Rhodamine 123 Preparation Products And Raw materials

Global( 246)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
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Triveni chemicals 08048762458 New Delhi, India 6088 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-81148696 +86-15536356810 China 3882 58 Inquiry
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BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569262 +86-15003564040 China 3256 58 Inquiry

Rhodamine 123 Spectrum

Rhodamine methyl ester hydrochloride Rhodamin 123 Chloride, laser grade 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride Rhodamine 123 ,98% RHODAMINE 123, 99+%, PURE Rhodamine 123, pure Rhodamine 123,2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester RhodaMine 123 Chloride, Laser Grade Rhodamine 123, 99+% 2-[6-AMINO-3-IMINO-3H-XANTHEN-9-YL]BENZOIC ACID METHYL ESTER 2-(6-AMINO-3-IMINO-3H-XANTHEN-9-YL)BENZOIC ACID METHYL ESTER CHLORIDE RHODAMINE METHYL ESTER CHLORIDE R 22420 R 302 Rhodamine 123 Chloride RHODAMINE 123, FOR FLUORESCENCE -Cellstain-Rh123 Rhodamine 123, pure, 99+% RHODAMINE 123 RHODAMINE 123 HYDROCHLORIDE 2-(6-amino-3-imino-3h-xanthen-9-yl)benzoicacidmethylestermonohydrochlorid 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-xanthyliuchloride 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)xanthyliumchloride benzoicacid,2-(6-amino-3-imino-3h-xanthen-9-yl)-,methylester,monohydroch Rhodamine 123 *CAS 62669-70-9* Rhodamine 123 (RH-123 rh123 3,6-DIAMINO-9-[2-(METHOXYCARBONYL)PHENYL]-10???XANTHEN-10-YLIUM CHLORIDE 62669-70-9 C21H17N2O3Cl C28H24N4O10S C21H16N2O3HCl C21H17ClN2O3 Fluorescent Probes, Labels, Particles and Stains Fluorescent Indicators and Probes Alphabetical Lipophilic and Membrane Probes Biochemicals and Reagents BioChemical Xanthene Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Fluorescent Labels & Indicators ROX