METHOTREXATE HYDRATE
- CAS No.
- 133073-73-1
- Chemical Name:
- METHOTREXATE HYDRATE
- Synonyms
- L-MTX;MTX HYDRATE;(+)Amethopterin;Antifolan hydrate;METHOTREXATE, VETEC;METHOTREXATE HYDRATE;Methotrexate xhydrate;L-AMETHOPTERIN HYDRATE;Methotrexate trihydrate;(+)AMETHOPTERINE HYDRATE
- CBNumber:
- CB2704227
- Molecular Formula:
- C20H24N8O6
- Molecular Weight:
- 472.46
- MOL File:
- 133073-73-1.mol
- Modify Date:
- 2023/6/8 9:02:12
| Melting point | 195 °C |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: insoluble |
| form | powder |
| color | yellow |
| optical activity | [α]/D +21.0±2.0° |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | FBOZXECLQNJBKD-ZDUSSCGKSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H360FD | |||||||||
| Precautionary statements | P201-P202-P264-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 61-25-36/38-46 | |||||||||
| Safety Statements | 53-26-36/37-45-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MA1225000 | |||||||||
| HS Code | 29339980 | |||||||||
| NFPA 704 |
|
METHOTREXATE HYDRATE price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M9929 | Methotrexate meets USP testing specifications | 133073-73-1 | 25MG | ₹11939.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9929 | Methotrexate meets USP testing specifications | 133073-73-1 | 100MG | ₹29270.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9929 | Methotrexate meets USP testing specifications | 133073-73-1 | 500MG | ₹78481.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A6770 | Methotrexate hydrate ≥98% (HPLC), powder | 133073-73-1 | 10MG | ₹4600.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A6770 | Methotrexate hydrate ≥98% (HPLC), powder | 133073-73-1 | 25MG | ₹7263.58 | 2022-06-14 | Buy |
METHOTREXATE HYDRATE Chemical Properties,Uses,Production
Description
Methotrexate (MTX) is similar in structure to folic acid and aminopterin . It acts by inhibiting the metabolism of folic acid and blocking key enzymes in the synthesis of purines and pyrimidines required for cell proliferation. MTX is known to induce adenosine release, which mediates many of its anti-inflammatory effects, including the reduction of proinflammatory cytokines. Formulations containing MTX have been used as immunosuppressants, in the treatment of cancer, autoimmune disease, ectopic pregnancy, and for the induction of medical abortions. MTX formulations have been considered the gold standard of disease-modifying antirheumatic drug (DMARD) therapy to treat both the immune-inflammatory and joint destructive processes of rheumatoid arthritis.
Chemical Properties
yellow to orange crystalline powder
Uses
Methotrexate hydrate has been used:
- as a dihydrofolate (DHFR)?inhibitor in sphere forming assay culture
- as a component of dulbecco′ modified Eagle′s medium (DMEM) for selection of transfected cells
- in viability and co-culture assays
METHOTREXATE HYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHOTREXATE HYDRATE Suppliers
Global( 113)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt. ltd | +91 8550986868 | Maharashtra, India | 736 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
133073-73-1(METHOTREXATE HYDRATE)Related Search:
METHOTREXATE HYDRATE CELL/INSECT CELL*CU LTURE TESTE
SU 4312
Folic acid
(+/-)AMETHOPTERIN
Methotrexate sodium
METHOTREXATE HYDRATE
7-CYANOMETHOTREXATE DIMETHYL ESTER
METHOTREXATE DIMETHYL ESTER
Dichloromethotrexate
7-HYDROXY METHOTREXATE
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l-4-amino-n10-methylpteroylglutamic acid
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4-Amino-10-methylfolic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, Methylaminopterin hydrate, MTX hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate
Methotrexate hydrate,4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methylaminopterin hydrate
Methotrexate hydrate,4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methotrexate hydrate, Methylaminopte
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Methotrexate trihydrate
METHOTREXATE, VETEC
(+)AMETHOPTERINE HYDRATE
(+)-AMETHOPTERIN HYDRATE
4-AMINO-10-METHYLFOLIC ACID HYDRATE
METHYLAMINOPTERIN HYDRATE
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L-(+)-AMETHOPTERIN HYDRATE
L-AMETHOPTERIN HYDRATE
MTX HYDRATE
L-MTX
L(+)-Amethopterin hydrate,99%
Antifolan hydrate
Methotrexate hydrate(1:x)
Methotrexate xhydrate
METHOTREXATE HYDRATE USP/EP/BP
Methotrexate hydrate, ≥98% (HPLC), powder
Methotrexate Hydrate (MTR), 98%
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, hydrate (9CI)
(+)Amethopterin
(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid hydrate(1:x)
Methotrexate Hydrate, ≥ 98.0%
133073-73-1
C20H22N8O5H2O
Complex Molecules
Chiral Building Blocks
Asymmetric Synthesis