Propacetamol
- CAS No.
- 66532-85-2
- Chemical Name:
- Propacetamol
- Synonyms
- Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N，N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
- CBNumber:
- CB2759429
- Molecular Formula:
- C14H20N2O3
- Molecular Weight:
- 264.32
- MOL File:
- 66532-85-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:04
| Melting point | 55-57 °C |
|---|---|
| Boiling point | 434.5±30.0 °C(Predicted) |
| Density | 1.132±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | H2O : 100 mg/mL (378.33 mM; Need ultrasonic) |
| pka | 14.20±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| CAS DataBase Reference | 66532-85-2(CAS DataBase Reference) |
Propacetamol Chemical Properties,Uses,Production
Description
Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.
Uses
Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.
Contact allergens
Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).
Propacetamol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
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| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | China | 5911 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15437 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | China | 13707 | 58 | Inquiry |