parsalmide
- CAS No.
- 30653-83-9
- Chemical Name:
- parsalmide
- Synonyms
- Parsal;MY-41-6;parsalmide;5-Amino-N-butyl-2-(2-propynyloxy)benzamide;5-Amino-N-butyl-2-(2-propyn-1-yloxy)benzamide;Benzamide, 5-amino-N-butyl-2-(2-propyn-1-yloxy)-
- CBNumber:
- CB2882635
- Molecular Formula:
- C14H18N2O2
- Molecular Weight:
- 246.3
- MOL File:
- 30653-83-9.mol
- Modify Date:
- 2023/5/4 17:34:37
parsalmide Chemical Properties,Uses,Production
Originator
Parsalmide,Shanghai Lansheng Corporation
Manufacturing Process
5-Acetylamino-2-acetoxybenzoyl chloride was obtained by reaction of 5acetylamino-2-acetoxy-benzoic acid with thionylchloride.
5-Acetylamino-N-butyl-2-hydroxybenzamide was produced in the result of treatment of 5-acetylamino-2-acetoxybenzoyl chloride with butylamine in the
presence of sodium hydroxide
5-Acetamino-N-(n-butyl)-2-propargyloxybenzamide was obtained by reaction of 5-acetylamino-N-butyl-2-hydroxybenzamide with propargylbromide in the presence of sodium, isopropyl alcohol and sulfuric acid.
28.8 g (0.1 mole) 5-acetamino-N-(n-butyl)-2-propargyloxybenzamide in 320 ml of 4 N sulfuric acid was heated, under stirring, at 90°-95°C for 2 h. The clear solution was cooled and its pH adjusted to 1 with 1 N NaOH; after filtering, further alkali was subsequently added until a pH of 10 was obtained. At this point the product was separated by filtration and recrystallized from ethanol at 60°C to give 16.6 g (a yield of 68%) of chromatographically pure 5-amino-N-(n-hutyl)-2-propargyloxybenzamide; melting point 85°-87°C.
Therapeutic Function
Muscle relaxant, Antiinflammatory, Analgesic
parsalmide Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
parsalmide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shanghai New Union Textra Import & Export Co., Ltd | +861-348-227-9455 | China | 2752 | 60 | Inquiry |
| Lanospharma Laboratories Co.,Ltd | 13440048448 | China | 6343 | 56 | Inquiry |
| Eurolabs Limited | 44 1625 850089 | United Kingdom | 6323 | 46 | Inquiry |
| ABI Chem | United States | 380 | 0 | Inquiry | |
| Shaanxi Didu New Material Co., Ltd | 029-63373950 15353716720 | China | 10011 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Shanghai New Union Textra Import & Export Co., Ltd | 60 |
| Lanospharma Laboratories Co.,Ltd | 56 |
| Eurolabs Limited | 46 |
| ABI Chem | 0 |
| Shaanxi Didu New Material Co., Ltd | 58 |