1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
- CAS No.
- 33301-41-6
- Chemical Name:
- 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
- Synonyms
- 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE;BUTTPARK 37\04-14;1-(Diphenylmethyl)-3-(mesyloxy)azetidine;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE;1-Benzhydryl-3-methanesulphonyloxyazetidine;1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98%;1-Benzhydryl-3-azetidinylMethanesulfonate>1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE CAS;1-DIPHENYLMETHYL-3-AZETIDINYL METHANESULFONATE
- CBNumber:
- CB3111828
- Molecular Formula:
- C17H19NO3S
- Molecular Weight:
- 317.4
- MOL File:
- 33301-41-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/17 13:48:25
Melting point | 111-112°C |
---|---|
Boiling point | 459.9±34.0 °C(Predicted) |
Density | 1.28±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Dichloromethane, Ether, Ethyl Acetate, Methanol |
form | Solid |
pka | 5.67±0.10(Predicted) |
color | White |
InChI | InChI=1S/C17H19NO3S/c1-22(19,20)21-16-12-18(13-16)17(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3 |
InChIKey | MSVZMUILYMLJCF-UHFFFAOYSA-N |
SMILES | N1(C(C2=CC=CC=C2)C2=CC=CC=C2)CC(OS(C)(=O)=O)C1 |
CAS DataBase Reference | 33301-41-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Safety Statements | 24/25 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
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1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
A proline analog and proline formation inhibitor
Synthesis
Preparation procedure of 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate: To a reaction flask was charged 632 g (2.64 mol) of 1-benzhydrylazetidin- 3-ol, acetonitrile (1.9 L), and triethylamine (601 g, 1.5 equiv). The mixture was cooled in an ice-acetone bath (-5 °C). Methanesulfonyl chloride (436 g, 1.20 equiv) was added via a drop funnel while keeping the reaction temperature at less than5 °C. HPLC showed reaction completion after 15 min. Water (6.3 L) was added, and the reaction mixture was stirred for 2 h at room temperature and filtered. The filter cake was rinsed with water (2 x 1 L), pulled dry under vacuum, and directly subjected to the amination reaction in the next step. Yield 100%.
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Sam Research Labs | +91 9873930190 | Hyderabad, India | 219 | 58 | Inquiry |
Azeocryst Organic Private Limited | +91-8879077780 +91-8879077780 | Maharashtra, India | 32 | 58 | Inquiry |
ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
Clarity Research Laboratory | +91-8008229325 +91-8008229325 | Telangana, India | 96 | 58 | Inquiry |
Synecos Organics Pvt. Ltd. | 08048372533Ext 588 | Pune, India | 20 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Bizten Impex Private Limited | +91 40-2351 0950 | Hyderabad, India | 71 | 58 | Inquiry |
Clarity Research Laboratory | 91-8008229325 | Hyderabad, India | 27 | 58 | Inquiry |
Bizten Impex Private Limited. | 91-40-23510950 | Hyderabad, India | 109 | 58 | Inquiry |
Azeocryst Organics Pvt., Ltd. | 91-22-26511513 | Maharashtra, India | 12 | 58 | Inquiry |