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1-(Diphenylmethyl)-3-azetidinyl methanesulfonate

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Structure
CAS No.
33301-41-6
Chemical Name:
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
Synonyms
1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE;BUTTPARK 37\04-14;1-(Diphenylmethyl)-3-(mesyloxy)azetidine;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE;1-Benzhydryl-3-methanesulphonyloxyazetidine;1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98%;1-Benzhydryl-3-azetidinylMethanesulfonate>1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE CAS;1-DIPHENYLMETHYL-3-AZETIDINYL METHANESULFONATE
CBNumber:
CB3111828
Molecular Formula:
C17H19NO3S
Molecular Weight:
317.4
MOL File:
33301-41-6.mol
MSDS File:
SDS
Modify Date:
2023/5/17 13:48:25

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Properties

Melting point 111-112°C
Boiling point 459.9±34.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Dichloromethane, Ether, Ethyl Acetate, Methanol
form Solid
pka 5.67±0.10(Predicted)
color White
InChI InChI=1S/C17H19NO3S/c1-22(19,20)21-16-12-18(13-16)17(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3
InChIKey MSVZMUILYMLJCF-UHFFFAOYSA-N
SMILES N1(C(C2=CC=CC=C2)C2=CC=CC=C2)CC(OS(C)(=O)=O)C1
CAS DataBase Reference 33301-41-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Safety Statements  24/25
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D4131 1-Benzhydryl-3-azetidinyl Methanesulfonate 33301-41-6 1G ₹15400 2022-05-26 Buy
Product number Packaging Price Buy
D4131 1G ₹15400 Buy

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

A proline analog and proline formation inhibitor

Synthesis

Preparation procedure of 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate: To a reaction flask was charged 632 g (2.64 mol) of 1-benzhydrylazetidin- 3-ol, acetonitrile (1.9 L), and triethylamine (601 g, 1.5 equiv). The mixture was cooled in an ice-acetone bath (-5 °C). Methanesulfonyl chloride (436 g, 1.20 equiv) was added via a drop funnel while keeping the reaction temperature at less than5 °C. HPLC showed reaction completion after 15 min. Water (6.3 L) was added, and the reaction mixture was stirred for 2 h at room temperature and filtered. The filter cake was rinsed with water (2 x 1 L), pulled dry under vacuum, and directly subjected to the amination reaction in the next step. Yield 100%.
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate synthesis

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Preparation Products And Raw materials

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BUTTPARK 37\04-14 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE 1-(DIPHENYLMETHYL)-3-(METHANESULFONYLOXY)AZETIDINE 1-DIPHENYLMETHYL-3-AZETIDINYL METHANESULFONATE 1-(diphenylmethyl)-3-(methanesulfonyloxy)azetinide 1-Diphenylmethyl-3-azetidinyl Methanethiosulfonate 1-Benzhydryl-3-methanesulphonyloxyazetidine 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98% Methanesulfonic acid 1-benzhydryl-azetidin-3-yl ester 1-(Diphenylmethyl)-3-(mesyloxy)azetidine 1-(Diphenylmethyl)-3-[(methylsulfonyl)oxy]azetidine 1-(Diphenylmethyl)azetidin-3-yl methanesulfonate 1-Benzhydryl-3-azetidinyl Methanesulfonate, 95% methanesulfonic acid [1-[di(phenyl)methyl]-3-azetidinyl] ester methanesulfonic acid [1-[di(phenyl)methyl]azetidin-3-yl] ester (1-benzhydryl-2-hydroxyazetidin-3-yl)methanesulfonate 1-(Diphenylmethyl)-3-azetidinyl methanesulfote 1-Benzhydrylazetidin-3-yl methanesulfonate 97% 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate 95% 1-Benzhydryl-3-azetidinylMethanesulfonate> 3-Azetidinol, 1-(diphenylmethyl)-, 3-methanesulfonate 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE CAS 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE 1-(Diphenylmethyl) azitidine-3-yl methane sulfonate Methane Sulphonic acid 1-Bezhydryl Azetidine 3-yl Ester 33301-41-6 3301-41-6 C17H19NO3S Aromatics Heterocycles MTS & Sulfhydryl Active Reagents