PALMITOYL COENZYME A POTASSIUM SALT

PALMITOYL COENZYME A POTASSIUM SALT Structure
CAS No.
1763-10-6
Chemical Name:
PALMITOYL COENZYME A POTASSIUM SALT
Synonyms
Palmityl-CoA;PALMITOYL-COA;Palmityl coenzyme A;Palmitoyl Coenzyme A;S-palmitoylcoenzyme A;Coenzyme A S-palmitate;Coenzyme A S-hexadecanoate;PALMITOYL COENZYME A, K SALT;coenzyme A palmitoyl derivative;PALMITOYL COENZYME A POTASSIUM SALT
CBNumber:
CB3200160
Molecular Formula:
C37H66N7O17P3S
Molecular Weight:
1005.94
MOL File:
1763-10-6.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:34

PALMITOYL COENZYME A POTASSIUM SALT Properties

storage temp. Store at 0°C
Density 1.54±0.1 g/cm3(Predicted)
pka 1.16±0.50(Predicted)

PALMITOYL COENZYME A POTASSIUM SALT Chemical Properties,Uses,Production

Chemical Properties

White powder

Purification Methods

Possible impurities are palmitic acid, S-palmitoyl thioglycolic acid and S-palmitoyl glutathione. These are removed by placing ca 200mg in a centrifuge tube and extracting with Me2CO (20mL), followed by two successive extractions with Et2O (15mL) to remove S-palmitoyl thioglycolic acid and palmitic acid. The residue is dissolved in H2O (4 x 4 mL), adjusted to pH 5 and centrifuged to remove insoluble S-palmitoyl glutathione and other insoluble impurities. To the clear supernatant is added 5% HClO4 (6mL) whereby S-palmitoyl CoA precipitates. The precipitate is washed with 0.8% HClO4 (10mL) and finally with Me2CO (3x 5mL) and dried in vacuo. It is stable for at least one year in dry form at 0o in a desiccator (dark). Solutions are stable for several months at -15o. Its solubility in H2O is 4%. The adenine content is used as the basis of purity with max at 260 and 232nm ( 6.4 x 106 and 9.4 x 106 cm2/mol, respectively). Higher absorption at 232nm would indicate other thio ester impurities, e.g. S-palmitoyl glutathione, which absorb highly at this wavelength. Also the phosphate content should be determined, and acid phosphate can be titrated potentiometrically. [Seubert Biochemical Preparations 7 80 1960, Srer et al. Biochim Biophys Acta 33 31 1959, Kornberg & Pricer J Biol Chem 204 329 , 345 1953, Beilstein 26 III/IV 3665.]

PALMITOYL COENZYME A POTASSIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

PALMITOYL COENZYME A POTASSIUM SALT Suppliers

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PALMITOYL COENZYME A, K SALT PALMITOYL COENZYME A POTASSIUM SALT N-HEXADECANOYL COENZYME A, POTASSIUM N-HEXADECANOYL COENZYME A POTASSIUM SALT S-palmitoylcoenzyme A [5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-hexadecanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy -phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid Palmityl-CoA Palmitoyl coenzyme A potassium salt≥ 88% (TLC) coenzyme A palmitoyl derivative Adenosine 3'-phosphoric acid 5'-[diphosphoric acid β-[(R)-3-hydroxy-4-[[3-[[2-(hexadecanoylthio)ethyl]amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl]] ester Coenzyme A S-hexadecanoate Coenzyme A S-palmitate Palmityl coenzyme A Palmitoyl Coenzyme A PALMITOYL-COA PALMITOYL COENZYME A POTASSIUM SALT(1763-10-6) 1763-10-6 C37H66N7O17P3S C37H65N7O17P3SK