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(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Structure
CAS No.
1161002-05-6
Chemical Name:
(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline
Synonyms
H37;G-15;RMB5;LUCA15;AGPAT1;1-AGPAT1;LPAAT-alpha;G15;G-15;G 15;1161002-05-6;RNA binding motif protein 5;Compound G15 - GPR30 antagonist
CBNumber:
CB32518797
Molecular Formula:
C19H16BrNO2
Molecular Weight:
370.24
MOL File:
1161002-05-6.mol
Modify Date:
2024/7/2 8:55:06
Request For Quotation

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Properties

Melting point 178-180 °C
Boiling point 462.7±45.0 °C(Predicted)
Density 1.472±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥37 mg/mL in DMSO
form solid
pka 3.98±0.40(Predicted)
color White to off-white

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) HPA048478 Anti-AGPAT1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody 1161002-05-6 100μL ₹41436.3 2022-06-14 Buy
Product number Packaging Price Buy
HPA048478 100μL ₹41436.3 Buy

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Chemical Properties,Uses,Production

Description

G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM). It displays low affinity cross-reactivity with the classical estrogen receptor (ER), ERα, so that at doses greater than 1 μM it is capable of mediating limited ER-dependent transcriptional activity. G-15 antagonizes the anti-depressive effects of estrogen in vivo.

Uses

(3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline is also known as “G-15”, a G-protein-coupled estrogen receptor antagonist designed for the treatment of estrogen-sensitive cancers.

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Suppliers

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career henan chemical co 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 58
DC Chemicals 58
Shanghai Maclean Biochemical Technology Co., LTD 58
Cayman Chemical Company 81
Shanghai Yifei Biotechnology Co. , Ltd. 58

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline Spectrum

(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline(1161002-05-6)1HNMR

1161002-05-6((3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline)Related Search:

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G-15 (3aS,4R,9bR)-4-(6-BroMo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline H37 LUCA15 RMB5 RNA binding motif protein 5 1-AGPAT1 AGPAT1 Anti-AGPAT1 antibody produced in rabbit LPAAT-alpha (3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline G15;G-15;G 15;1161002-05-6 (3aR,4R,9bS)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (G-15) 3H-Cyclopenta[c]quinoline, 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-, (3aS,4R,9bR)- Compound G15 - GPR30 antagonist (3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline Inhibitor,inhibit,G-15,G15,Estrogen Receptor/ERR,G 15 1161002-05-6