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Phlorizin dihydrate

Phlorizin dihydrate Structure
CAS No.
7061-54-3
Chemical Name:
Phlorizin dihydrate
Synonyms
PHLORIDZIN;PHLORIDZIN(RG);Phlorizin dihydrate;TIMTEC-BB SBB005924;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phloretin 2'-b-D-glucopyranoside;Phlorizin, Dihydrate, FroM Apple Wood
CBNumber:
CB3331802
Molecular Formula:
C21H26O11
Molecular Weight:
454.43
MOL File:
7061-54-3.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:06

Phlorizin dihydrate Properties

Melting point 113-114 °C(lit.)
alpha -52 º (c=3, EtOH)
storage temp. Inert atmosphere,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Solid
color White to off-white
optical activity [α]20/D 52°, c = 3 in ethanol
BRN 66621
CAS DataBase Reference 7061-54-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UC2080000
3-10-23

Phlorizin dihydrate price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 100MG ₹5997.05 2022-06-14 Buy
Sigma-Aldrich(India) P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 500MG ₹7739.88 2022-06-14 Buy
Sigma-Aldrich(India) P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 1G ₹12394.63 2022-06-14 Buy
Sigma-Aldrich(India) P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 5G ₹38959.18 2022-06-14 Buy
Sigma-Aldrich(India) P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 10G ₹67309.85 2022-06-14 Buy
Product number Packaging Price Buy
P3449 100MG ₹5997.05 Buy
P3449 500MG ₹7739.88 Buy
P3449 1G ₹12394.63 Buy
P3449 5G ₹38959.18 Buy
P3449 10G ₹67309.85 Buy

Phlorizin dihydrate Chemical Properties,Uses,Production

Uses

Phloridzin dihydrate has been used as:

  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Biochem/physiol Actions

Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.

Phlorizin dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 162)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16858 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503282 China 8822 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 11506 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13164 58 Inquiry
Phlorizin dihydrate 1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate 2'-O-GLUCOSYL-4',6',4-TRIHYDROXYDIHYDROCHALCONE 1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate TIMTEC-BB SBB005924 PHLORETIN-2'-BETA-D-GLUCOSIDE phloridzin from apple wood 1-[2-(β-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone PHLORIDZIN(RG) Phlorizin dihydrate Phloretin 2μ-β-D-glucopyranoside, Phloretin 2μ-β-D-glucoside, 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone Phloridzin dihydrate,1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin 2′-β-D-glucopyranoside, Phloretin 2′-β-D-glucoside, Phlorizin dihydrate Phlorizin, Dihydrate, FroM Apple Wood Phloridzin dihydrate 99% Phloretin 2'-b-D-glucopyranoside 1-[2,4-dihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]phenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate 1-(2,4-Dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one dihydrate Phlorizin dihydrate USP/EP/BP 1-Propanone,1-[2-(b-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-,dihydrate PHLORIDZIN 7061-54-3 C21H24O10x2H2O C21H24O102H2O C21H28O12 Glycosides Sugars Carbohydrate Synthesis Biochemicals and Reagents Analytical Standards BioChemical Analytical Chromatography Product Catalog Natural Dyes Monosaccharides Specialty Synthesis Forensic and Veterinary Standards Drug Standards Chromatography Natural Plant Extract