Phosalone
- CAS No.
- 2310-17-0
- Chemical Name:
- Phosalone
- Synonyms
- p974;zolon;P 974;p-974;ZOLONE;Zoolon;AZOFENE;11974rp;fosalon;Fozalon
- CBNumber:
- CB3358140
- Molecular Formula:
- C12H15ClNO4PS2
- Molecular Weight:
- 367.81
- MOL File:
- 2310-17-0.mol
- Modify Date:
- 2023/5/18 11:31:05
| Melting point | 47.5-48° |
|---|---|
| Boiling point | 446.7±55.0 °C(Predicted) |
| Density | 1.39 g/cm3 |
| vapor pressure | <6×10-5 Pa (25 °C) |
| Flash point | 100 °C |
| storage temp. | 0-6°C |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | -1.75±0.20(Predicted) |
| Water Solubility | 3.05 mg l-1 (25°C) |
| form | solid |
| color | Crystals |
| Odor | garlic odor |
| BRN | 694650 |
| Stability | Hygroscopic |
| InChIKey | IOUNQDKNJZEDEP-UHFFFAOYSA-N |
| CAS DataBase Reference | 2310-17-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Phosalone(2310-17-0) |
| EPA Substance Registry System | Phosalone (2310-17-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311-H317-H332-H410 |
| Precautionary statements | P261-P273-P280-P301+P310-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | T,N |
| Risk Statements | 21-25-50/53-43-20/21 |
| Safety Statements | 36/37-45-60-61 |
| RIDADR | 2783 |
| WGK Germany | 3 |
| RTECS | TD5175000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 in mice, female, male rats, guinea pigs (mg/kg): 180-205, 135-170, 120, 82-150 orally; female rats (mg/kg): 390 dermally (Colinese, Terry) |
Phosalone Chemical Properties,Uses,Production
Uses
Phosalone is a organophosphate compouund used as insecticide and acaricide. Phosalone is a weak inhibitor of acetylcholinesterase.
Definition
ChEBI: A member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide.
Safety Profile
Poison by ingestion, skin contact,and possibly other routes. A cholinesterase inhibitor. Seealso PARATHION. When heated to decomposition itemits very toxic fumes of Cl-, NOx, POx, and SOx.
Environmental Fate
Plant. Degrades in plants to chlorbenzoxazolone, formaldehyde and diethyl phosphorodithioate (Hartley and Kidd, 1987)
Soil. Ambrosi et al. (1977a) studied the persistence and metabolism of phosalone in
both moist and flooded Matapeake loam and Monmouth fine sandy loam. Phosalone rapidly
degraded (half-life 3 to 7 days) but mineralization to carbon dioxide accoun
Chemical/Physical. Emits toxic fumes of chlorine, phosphorus, nitrogen and sulfur
oxides when heated to decomposition (Sax and Lewis, 1987)
Metabolic pathway
Photodegradation of phosalone in solvent yields dechlorinated phosalone. Irradiation in methanol affords O,O-diethyl-S-methylphosphorothioate and 6- chloro-3-methoxymethyl-2-oxobenzoxazoline with other common products. Photolysis of phosalone in the solid state as a thin film on a glass surface produces a number of photoproducts including 6-chloro-3- mercaptomethyl-2-oxobenzoxazoline and its dimeric disulfide.
Metabolism
Orally administered phosalone in mammals is rapidly degraded by oxidation and hydrolysis to give O,O-diethyl hydrogen phosphorothioate and phosphorodithioate and 6-chloro-2,3-dihydro-2-oxobenzoxazole, which is further metabolized and excreted in the urine. It is strongly adsorbed to soil and rapidly degraded with DT50 values of 1–4 d.
Phosalone Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Parijat Industries India Private Limited | 08048372460Ext 265 | Delhi, India | 19 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Verma Traders | 08069033856Ext 822 | Uttar Pradesh, India | 1 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29900 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12962 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
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