PROSTAGLANDIN A1
- CAS No.
- 14152-28-4
- Chemical Name:
- PROSTAGLANDIN A1
- Synonyms
- PGA1;Prostaglandin A;Prostagladin E1;C04685;pga(sub1);pga(sup1);Prostagladin A;PROSTAGLANDIN A1;PROSTAGLANDINS A1;prostaglandina(sup1)
- CBNumber:
- CB3666883
- Molecular Formula:
- C20H32O4
- Molecular Weight:
- 336.47
- MOL File:
- 14152-28-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:01:57
| Melting point | 43°C |
|---|---|
| Boiling point | 392.93°C (rough estimate) |
| Density | 1.0192 (rough estimate) |
| refractive index | 1.4434 (estimate) |
| storage temp. | -20°C |
| solubility | acetone: 10 mg/mL, clear |
| form | White solid. |
| pka | 4.77±0.10(Predicted) |
| color | Off-white |
| BRN | 2003401 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H360F | |||||||||
| Precautionary statements | P201-P301+P312+P330-P308+P313 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GY5977900 | |||||||||
| F | 8-10 | |||||||||
| HS Code | 2937500000 | |||||||||
| NFPA 704 |
|
PROSTAGLANDIN A1 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P7265 | Prostaglandin A1 synthetic | 14152-28-4 | 1MG | ₹16259.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7265 | Prostaglandin A1 synthetic | 14152-28-4 | 5MG | ₹49188.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7265 | Prostaglandin A1 synthetic | 14152-28-4 | 10MG | ₹78340.53 | 2022-06-14 | Buy |
PROSTAGLANDIN A1 Chemical Properties,Uses,Production
Description
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-
Uses
Prostaglandin A1 has been shown to inhibit human immunodeficiency virus type 1 (HIV-1) replication in various cell types. In addition, as a precursor to the anti-inflammatory prostaglandins, it activates pro-inflammatory PGD2 receptor CRTH2 initiating the anti-inflammatory response.
General Description
Prostaglandin A1(PGA1) belongs to the class of cyclopentenone prostaglandin. PGA1 is generated by the dehydration of prostaglandin E1 (PGE1).
Enzyme inhibitor
This eicosanoid (FWfree-acid = 336.47 g/mol; CAS 14152-28-4; Symbol: PGA1) induces apoptosis and stimulates the expression of stress genes. The structure and role of the prostaglandin A1 was investigated by Bergstr?m and Samuelsson, who shared the 1982 Nobel Prize in Physiology or Medicine for their pioneering work on the eicosanoids. Target(s): CYP4F2; DNA topoisomerase II; HIV-1 transcription; 3ahydroxysteroid dehydrogenase, NADP+-dependent; IkB kinase; Mayaro virus replication; stress-induced NF-kB activation; and virus protein biosynthesis, or translation.
PROSTAGLANDIN A1 Preparation Products And Raw materials
Raw materials
Preparation Products
PROSTAGLANDIN A1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | China | 992 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Huigen Biotech (Shanghai) Co., Ltd. | 13761582449 | China | 204 | 58 | Inquiry |
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