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PROSTAGLANDIN J2

PROSTAGLANDIN J2 Structure
CAS No.
60203-57-8
Chemical Name:
PROSTAGLANDIN J2
Synonyms
PGJ2;Aids058772;Aids-058772;PROSTAGLANDIN J2;PGJ2 (Prostaglandin J2);Prostaglandin J2 (PGJ2);9-deoxy-delta-9-prostaglandind2;Prostaglandin J2 Lipid Maps MS Standard;PROSTAGLANDIN J2, 5MG/ML IN METHYL ACETA;11-OXO-15S-HYDROXY-PROSTA-5Z,9,13E-TRIEN-1-OIC ACID
CBNumber:
CB4477024
Molecular Formula:
C20H30O4
Molecular Weight:
334.45
MOL File:
60203-57-8.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:09

PROSTAGLANDIN J2 Properties

Boiling point 521.7±50.0 °C(Predicted)
Density 1.103±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-.DEL
pka 4.75±0.10(Predicted)
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319-H336
Precautionary statements  P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard Codes  Xn,Xi,F
Risk Statements  20/21/22-36/37/38-67-66-36-11
Safety Statements  26-36-33-29-16
NFPA 704
3
2 0

PROSTAGLANDIN J2 Chemical Properties,Uses,Production

Description

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines. However, this activity has been attributed to further metabolites of PGJ2 and not the parent compound itself.

Uses

PGJ2 (Prostaglandin J2) is a Prostaglandin D2 metabolite that has shown potent anti-neoplastic and antiviral activity.

Definition

ChEBI: A member of the class of prostaglandins J that consists of prosta-5,9,13-trien-1-oic acid substituted by an oxo group at position 11 and a hydroxy group at position 15 (the 5Z,13E,15S stereoisomer).

PROSTAGLANDIN J2 Preparation Products And Raw materials

Raw materials

Preparation Products

PROSTAGLANDIN J2 Suppliers

Global( 39)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 China 25009 65 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28070 58 Inquiry
Shanghai Universal Biotech Co.,Ltd 18768175414 China 24998 58 Inquiry
Hubei Aiputi Bioengineering Co., Ltd. 17762444226 China 2402 58 Inquiry
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169085 China 27996 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8736 58 Inquiry
11-OXO-15S-HYDROXY-PROSTA-5Z,9,13E-TRIEN-1-OIC ACID (5Z,13E,15S)-15-HYDROXY-11-OXOPROSTA-5,9,13-TRIEN-1-OIC ACID PROSTAGLANDIN J2 PGJ2 9-deoxy-delta-9-prostaglandind2 PROSTAGLANDIN J2, 5MG/ML IN METHYL ACETA (Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxo-1-cyclopent-2-enyl]hept-5-enoic acid (5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9,13-triene-1-oic acid Aids058772 Aids-058772 Prosta-5,9,13-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,13E,15S)- Prostaglandin J2 Lipid Maps MS Standard PGJ2 (Prostaglandin J2) Prostaglandin J2 (PGJ2) 60203-57-8