ChemicalBook > Product Catalog >API >Antibiotics >Cephalosporins Drugs >Sodium cefamandole

Sodium cefamandole

Sodium cefamandole Structure
CAS No.
30034-03-8
Chemical Name:
Sodium cefamandole
Synonyms
sodium cefamandole;CEFAMANDOLE SODIUM;Cephamandole sodium;CEFAMANDOLE SODIUM SALT;Cefamandole Sodium (250 mg);Sodium cefamandole USP/EP/BP;monosodiumsalt,d-hyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-mandelamido-3-(((1-met;Sodium 7-D-mandelamido-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-mandelamido-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, D- (8CI)
CBNumber:
CB3744569
Molecular Formula:
C18H17N6NaO5S2
Molecular Weight:
484.48
MOL File:
30034-03-8.mol
Modify Date:
2023/6/8 9:02:24

Sodium cefamandole Properties

Melting point >175°C (dec.)
storage temp. Store at RT.
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Pale Yellow
Stability Moisture Sensitive
CAS DataBase Reference 30034-03-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS07
Signal word  Danger
Hazard statements  H335-H319-H315-H334-H317
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P261-P285-P304+P341-P342+P311-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard Codes  Xn
Risk Statements  36/37/38-42/43
Safety Statements  26-36
WGK Germany  2
RTECS  XI0389000
Toxicity mouse,LD50,intravenous,4460mg/kg (4460mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984.
NFPA 704
0
2 0

Sodium cefamandole Chemical Properties,Uses,Production

Description

Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus. It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.

Chemical Properties

White Solid

Uses

Broad-spectrum semi-synthetic cephalosporin antibiotic.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefamandole.

Sodium cefamandole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 103)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21675 55 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt CEFAMANDOLE SODIUM CEFAMANDOLE SODIUM SALT 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-mandelamido-3-(((1-met monosodiumsalt,d-hyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo (6R,7R)-7-[(R)-2-Hydroxy-2-phenylacetylamino]-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Cephamandole sodium Cefamandole Sodium (250 mg) sodium [6r-[6alpha,7beta(r*)]]-7-[[(formyloxy)phenylacetyl]amino]-3-[[(1-methyl-1h-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sodium (6r-(6alpha,7beta(r*)))-7-((hydroxyphenylacetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate sodium cefamandole 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, [6R-[6α,7β(R*)]]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-hydroxyphenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7R)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-mandelamido-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, D- (8CI) Sodium 7-D-mandelamido-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate Sodium cefamandole USP/EP/BP 30034-03-8 C18H17N6O5S2Na C18H17N6NaO5S2 48448 BioChemical Antibiotics Antibiotics A to Z Antibiotics A-F A - KAntibiotics Antibacterial Antibiotics A to Antibiotics A-FAntibiotics Chemical Structure Class Interferes with Cell Wall SynthesisAntibiotics Mechanism of Action Penicillins and Cephalosporins (beta-Lactams) Spectrum of Activity Nucleotides and Nucleosides Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Sulfur & Selenium Compounds