Bromadiolone
- CAS No.
- 28772-56-7
- Chemical Name:
- Bromadiolone
- Synonyms
- BROPRODIFACOUM;MAKI;Miki;Musal;Roban;boldo;lm637;rafix;temus;eradic
- CBNumber:
- CB3756243
- Molecular Formula:
- C30H23BrO4
- Molecular Weight:
- 527.41
- MOL File:
- 28772-56-7.mol
- Modify Date:
- 2024/3/14 15:18:26
| Melting point | 200-210° |
|---|---|
| Boiling point | 723.4±60.0 °C(Predicted) |
| Density | 1.3243 (rough estimate) |
| vapor pressure | 2 x l0-6Pa (20 °C) |
| refractive index | 1.4490 (estimate) |
| storage temp. | -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| Water Solubility | 19 mg l-1 (20 °C) |
| form | Powder |
| pka | 4.04(at 21℃) |
| Merck | 13,1366 |
| BRN | 1335336 |
| LogP | 7.480 (est) |
| CAS DataBase Reference | 28772-56-7(CAS DataBase Reference) |
| EPA Substance Registry System | Bromadiolone (28772-56-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H310+H330-H360D-H372-H410 | |||||||||
| Precautionary statements | P202-P264-P273-P280-P302+P352+P310-P304+P340+P310 | |||||||||
| Hazard Codes | T+,N | |||||||||
| Risk Statements | 27/28-50 | |||||||||
| Safety Statements | 28-36/37/39-45-61 | |||||||||
| RIDADR | UN 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GN4934700 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | I | |||||||||
| Toxicity | LD50 in rats, mice (mg/kg): 1.125, 1.75 orally (Grand) | |||||||||
| NFPA 704 |
|
Bromadiolone Chemical Properties,Uses,Production
Description
Bromadiolone is used to control rodents around buildings, inside transport vehicles and sewers. It is often formulated as meal bait, rat and mouse bait ready-to-use place packs, paraffinized pellets and blocks.
Chemical Properties
Bromadiolone is white to off-white (yellowish) powder.
Occurrence
Boldo is an evergreen found in Chile, Peru, and Morocco.
Uses
Bromadiolone is an anticoagulant rodenticide used on non-crop areas.
General Description
Yellowish powder. Used as an anticoagulant rodenticide.
Health Hazard
The compound is toxic by oral exposure.
Fire Hazard
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, Bromadiolone emits toxic fumes of bromine containing compounds.
Agricultural Uses
Rodenticide: Bromadiolone is used as an anticoagulant rodenticide and used as bait for rodent control against house mice, roof rats and warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the Federal meat, poultry, shell egg grading and egg products inspection program.
Trade name
BOLDO®; BOOT HILL®; BROMONE®; CANADIEN 2000®; CONTRAC®; HAWK®; LM- 637®; MAKI®; RAT ARREST®; RAT FREE®; RATIMUS®; RENTOKIL DEADLINE®; SLAYMOR®; SUPER-CAID®; SUPER-ROZOL®; SUP'ORATS®; TERMUS®
Potential Exposure
Bromadiolone is used as an anticoagulant rodenticide. It is bait for rodent control used against house mice, roof rats, warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the federal meat, poultry, shell egg grading, and egg products inspection program. May be used as a drug.
Environmental Fate
Bromadiolone belongs to second generation of long-acting anticoagulant rodenticide. It acts by interfering with the prothrombin synthesis by blocking the regeneration of vitamin K dependant proteins in the liver and thereby disrupting the clotting mechanisms and increasing the tendency to hemorrhages and subsequent death.
Metabolic pathway
Metabolism in the rat is very slow and products other than a conjugate of the parent compound have not been identified. Biodegradation in soil and plants has not been reported.
Shipping
UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials. UN3026 Coumarin derivative pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.
Bromadiolone Preparation Products And Raw materials
Raw materials
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