ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Metabolism >P450 (e.g. CYP17) inhibitor >Avasimibe
Avasimibe
- CAS No.
- 166518-60-1
- Chemical Name:
- Avasimibe
- Synonyms
- CS-90;CI-1011;avasimibe;PD 148515;Ava Maibu;Avasimibe, >=98%;Avasimibe(CI-1011);Avasimibe USP/EP/BP;PD-148515|||CI-1011;Avasimibe Solution, 100ppm
- CBNumber:
- CB3854950
- Molecular Formula:
- C29H43NO4S
- Molecular Weight:
- 501.72
- MOL File:
- 166518-60-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
Avasimibe price More Price(2)
Avasimibe Chemical Properties,Uses,Production
Uses
Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasimibe is known to induce apoptosis of glioma cell lines as a model of glioblastoma.
Biochem/physiol Actions
Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor. It was originally developed as an antilepic drug, and was shown to significantly reduce plasma total triglyceride and VLDL-cholesterol, but later clinical trials were disappointing. ACAT has also been investigated as a potential therapeutic target for Alzheimer′s disease. Recent studies have looked at the effects of avasimibe in reducing amyloid pathology by limiting generation and increasing clearance of diffusible amyloid-beta (Abeta).
Avasimibe Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 128)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25247 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
166518-60-1(Avasimibe)Related Search:
Avasimibe, >=98%
2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate
[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid
PD 148515
avasimibe
n-(2,6-dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide
N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE
((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER
Avasimibe(CI-1011)
CI-1011
AVASIMIBE;CI-1011; PD 148515
Sulfamic acid,N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenylester
1-[(2,6-DIISOPROPYLPHENOXYSULFONYL)AMINO]-2-(2,4,6-TRIISOPROPYLPHENYL)ETHANONE
Ava Maibu
CS-90
Avasimibe Solution, 100ppm
Avasimibe USP/EP/BP
1-({[2,6-bis(propan-2-yl)phenoxy]sulfonyl}amino)-2-[2,4,6-tris(propan-2-yl)phenyl]ethan-1-one
PD-148515|||CI-1011
166518-60-1
C29H43NO4S
Inhibitors