Buclosamide

Buclosamide Structure
CAS No.
575-74-6
Chemical Name:
Buclosamide
Synonyms
Fungit;Demycin;Buclosamide;Buclosamidum;3004 BUCLOSAMIDE;N-butyl-4-chlorosalicylamide;N-Butyl-4-chloro-2-hydroxybenzamide;Benzamide, N-butyl-4-chloro-2-hydroxy-
CBNumber:
CB3875443
Molecular Formula:
C11H14ClNO2
Molecular Weight:
227.69
MOL File:
575-74-6.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

Buclosamide Properties

Melting point 90-92°
Boiling point 366.6±32.0 °C(Predicted)
Density 1.1769 (rough estimate)
refractive index 1.5500 (estimate)
pka 7.43±0.35(Predicted)

Buclosamide Chemical Properties,Uses,Production

Originator

Fungit,Dragon

Manufacturing Process

4-Chloro-2-hydroxy-benzoic acid n-butyl-amide
A mixture consisting of 114 g of 4-chloro-2-hydroxy-benzoic acid n-butylester, 64 grams of methanol and 130 g of n-butyl-amine is heated for 22 hours at 80°C; then the parts volatile up to 130°C are distilled off under reduced pressure. The residue crystallizing in the cold is dissolved in 200 ml of methanol and the solution obtained is slowly added dropwise and while stirring into dilute hydrochloric acid, if necessary, after treatment with animal charcoal. The precipitate which is at first semi-solid soon crystallizes completely. It is filtered with suction, washed with dilute hydrochloric acid, then thoroughly washed again with water, and the product obtained in good yield is dried in the air. After having been recrystallized twice from carbon tetrachloride the 4-chloro-2-hydroxybenzene acid n-butylamide melts at 90- 92°C.

Therapeutic Function

Antifungal

Buclosamide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 24)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 2417 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503259 +86-19930503259 China 18444 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9971 58 Inquiry
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 China 955 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 China 40041 58 Inquiry
Fungit Buclosamide N-butyl-4-chlorosalicylamide N-Butyl-4-chloro-2-hydroxybenzamide 3004 BUCLOSAMIDE Demycin Buclosamidum Benzamide, N-butyl-4-chloro-2-hydroxy- 575-74-6 5475-74-6