Dibutyl phthalate
- CAS No.
- 84-74-2
- Chemical Name:
- Dibutyl phthalate
- Synonyms
- DBP;DI-N-BUTYL PHTHALATE;Bis-n-butyl Phthalate;Bufa;dibutyl-o-phthalate;PHTHALIC ACID DIBUTYL ESTER;PHTHALIC ACID, BIS-BUTYL ESTER;Palatinol C;ARALDITE RESIN;Dibutylphthalat
- CBNumber:
- CB7161937
- Molecular Formula:
- C16H22O4
- Molecular Weight:
- 278.34
- MOL File:
- 84-74-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | -35 °C (lit.) |
|---|---|
| Boiling point | 340 °C (lit.) |
| Density | 1.043 g/mL at 25 °C (lit.) |
| vapor density | 9.6 (vs air) |
| vapor pressure | 1 mm Hg ( 147 °C) |
| refractive index |
n |
| Flash point | 340 °F |
| storage temp. | 2-8°C |
| solubility | Very soluble in alcohol, ether, acetone, benzene |
| form | Liquid |
| Specific Gravity | 1.049 (20/20℃) |
| color | APHA: ≤10 |
| Relative polarity | 0.272 |
| Odor | odorless |
| explosive limit | 0.47%, 236°F |
| Water Solubility | Slightly soluble. 0.0013 g/100 mL |
| FreezingPoint | -35℃ |
| Merck | 14,3035 |
| BRN | 1914064 |
| Henry's Law Constant | 6.3 x 10-5 atm?m3/mol (quoted, Petrasek et al., 1983) |
| Exposure limits | NIOSH REL: TWA 5 mg/m3, IDLH 4,000 mg/m3; OSHA PEL: TWA 5 mg/m3; ACGIH TLV: TWA 5 mg/m3. |
| Dielectric constant | 6.0（45℃） |
| InChIKey | DOIRQSBPFJWKBE-UHFFFAOYSA-N |
| LogP | 4.46-4.57 at 20-30℃ |
| CAS DataBase Reference | 84-74-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Dibutyl phthalate(84-74-2) |
| EPA Substance Registry System | Dibutyl phthalate (84-74-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H360FD-H410 | |||||||||
| Precautionary statements | P201-P273-P308+P313 | |||||||||
| Hazard Codes | T,N,F | |||||||||
| Risk Statements | 61-50-62-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 53-45-61-36/37-16 | |||||||||
| OEB | B | |||||||||
| OEL | TWA: 5 mg/m3 | |||||||||
| RIDADR | UN 3082 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | TI0875000 | |||||||||
| Autoignition Temperature | 756 °F | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29173100 | |||||||||
| Toxicity | Acute oral LD50 for rats 8,000 mg/kg (RTECS, 1985). | |||||||||
| IDLA | 4,000 mg/m3 | |||||||||
| NFPA 704 |
|
Dibutyl phthalate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 524980 | Dibutyl phthalate 99% | 84-74-2 | 25ML | ₹3897 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 524980 | Dibutyl phthalate 99% | 84-74-2 | 100ML | ₹4308.35 | 2022-06-14 | Buy |
| Sigma-Aldrich | 524980 | Dibutyl phthalate 99% | 84-74-2 | 500ML | ₹4957.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 524980 | Dibutyl phthalate 99% | 84-74-2 | 500ML | ₹4957.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 524980 | Dibutyl phthalate 99% | 84-74-2 | 1L | ₹5953.75 | 2022-06-14 | Buy |
Dibutyl phthalate Chemical Properties,Uses,Production
Description
Dibutyl phthalate is included as an insect repellent in some aerosol sprays used to treat flystrike in sheep. It is colorless oily liquid with a very weak aromatic odor.
Chemical Properties
Dibutyl phthalate occurs as an odorless, oily, colorless, or very slightly yellow-colored, viscous liquid.
Physical properties
Colorless to pale yellow, oily, viscous liquid with a mild, aromatic odor
Uses
Dibutyl phthalate is used in plasticizers, cosmetics, safety glass, insecticides, printing inks, paper coatings, adhesives, elastomers and explosives; solvent in polysulfide dental impression materials; solvent for perfume oils; perfume fixative; textile lubricating agent; solid rocket propellent; emollient in aerosol antiperspirants; insect repeller; plasticizer in various plastic materials.
Production Methods
Dibutyl phthalate is produced from n-butanol and phthalic anhydride in an ester formation reaction.
Definition
ChEBI: Dibutyl phthalate is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans. It has a role as an environmental contaminant, a teratogenic agent, a plasticiser, a metabolite and an EC 3.2.1.20 (alpha-glucosidase) inhibitor. It is a phthalate ester and a diester. It is functionally related to a butan-1-ol.
General Description
Dibutyl phthalate is a colorless oily liquid. Dibutyl phthalate is insoluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since Dibutyl phthalate is a liquid Dibutyl phthalate can easily penetrate the soil and contaminate groundwater and nearby streams. Dibutyl phthalate is combustible though Dibutyl phthalate may take some effort to ignite. Dibutyl phthalate is used in paints and plastics and as a reaction media for chemical reactions.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Dibutyl phthalate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Avoid contact with strong oxidizing agents and strong bases. Will not polymerize. [USCG, 1999]. Can generate electrostatic charges. [Handling Chemicals Safely 1980. p. 250].
Health Hazard
The toxicity of this compound is very low. Inhumans, oral intake of dibutyl phthalate at adose level of 150 mg/kg may cause nausea,vomiting, dizziness, hallucination, distortedvision, lacrimation, and conjunctivitis withprompt recovery. It metabolizes to monobutylester and phthalic acid and is excreted in urine.The inhalation toxicity should be insignificantbecause of its negligible low vapor pressure[<0.1 torr at 20°C (68°F)]. However, expo sure to its mist or aerosol can cause irritationof eyes and mucous membranes
LD50 value, oral (mice): 5300 mg/kg.
Fire Hazard
Combustible.
Pharmaceutical Applications
Dibutyl phthalate is used in pharmaceutical formulations as a plasticizer in film-coatings. It has been evaluated as a pore-forming agent in novel delivery systems.It is also used extensively as a solvent, particularly in cosmetic formulations such as antiperspirants, hair shampoos, and hair sprays. In addition to a number of industrial applications, dibutyl phthalate is used as an insect repellent, although it is not as effective as dimethyl phthalate.
Contact allergens
It is mainly used as a nonreactive epoxy diluent.
Safety Profile
Moderately toxic by intraperitoneal and intravenous routes. Mildly toxic by ingestion. Human systemic eye effects by ingestion, hallucinations, dstorted perceptions, nausea or vomiting, and kidney, ureter, or bladder changes. Experimental teratogenic and reproductive effects. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. Violent reaction with Cl2. Incompatible with chlorine. To fight fire, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and fumes. See also ESTERS, PHTHALIC ACID, and n BUTYL ALCOHOL.
Safety
Dibutyl phthalate is generally regarded as a relatively nontoxic material, although it has occasionally been reported to cause hypersensitivity reactions. It is widely used in topical cosmetic and some oral pharmaceutical formulations.
LD50 (mouse, IV): 0.72g/kg
LD50 (mouse, oral): 5.3g/kg
LD50 (rat, oral): 8.0g/kg
LD50 (rat, IP): 3.05mL/kg
storage
Dibutyl phthalate should be stored in a well-closed container in a cool, dry, location. Containers may be hazardous when empty since they can contain product residues such as vapors and liquids.
Purification Methods
Wash DBP with H2O (to free it from alcohol), then dilute NaOH (to remove any butyl hydrogen phthalate or acid), aqueous NaHCO3 (charcoal), then distilled water. Dry it (CaCl2), distil it at 10torr or less, and store it in a desiccator over P2O5. [Beilstein 9 II 586, 9 III 4102, 9 IV 3175.]
Incompatibilities
Dibutyl phthalate reacts violently with chlorine. It also reacts with oxidizing agents, acids, bases, and nitrates.
Regulatory Status
Included in the FDA Inactive Ingredients Database (oral capsules, delayed action, enteric coated, and controlled release tablets). Included in nonparenteral medicines licensed in the UK (oral capsules, tablets, granules; topical creams and solutions).
Dibutyl phthalate Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| ADVENT CHEMBIO PRIVATE LIMITED | +91-9821524116 +91-9821524116 | Mumbai, India | 353 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| KLJ Group | +91-1141427427 +91-1145371400 | New Delhi, India | 29 | 58 | Inquiry |
| Rachna Plasticizers | +91-2226480230 +91-2226480230 | Maharashtra, India | 6 | 58 | Inquiry |
| Lucknow Organics Pvt Ltd | +91-5224005505 +91-5224005505 | Uttar Pradesh, India | 8 | 58 | Inquiry |
| Nayakem Organics Pvt. Ltd | +91-022-24314854 +91-2224314854 | Maharashtra, India | 15 | 58 | Inquiry |
| Supreme Plasticizers | +91-9845114149 +91-9845170909 | Maharashtra, India | 3 | 58 | Inquiry |
| Lalitha Chem Industries Pvt Ltd | +91-9767041261 +91-9767041261 | Gujarat, India | 16 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| ADVENT CHEMBIO PRIVATE LIMITED | 58 |
| JSK Chemicals | 58 |
| UNILOSA INTERNATINAL PRIVATE LIMITED | 58 |
| KLJ Group | 58 |
| Rachna Plasticizers | 58 |
| Lucknow Organics Pvt Ltd | 58 |
| Nayakem Organics Pvt. Ltd | 58 |
| Supreme Plasticizers | 58 |
| Lalitha Chem Industries Pvt Ltd | 58 |
Related articles
- Dibutyl Phthalate: Applications as Plasticizer and Antiandrogenic Effects
- Dibutyl phthalate, a common plasticizer, has significant antiandrogenic effects, impacting maternal health, fetal development,....
- May 16，2024
- Dibutyl phthalate: Degratation, applications and toxicity
- Dibutyl phthalate (DBP) is an organic compound which is commonly used as a plasticizer because of its low toxicity and wide li....
- Jun 27，2023
- Dibutyl phthalate-Application, Uses, Toxicity, Mechanism of action
- Dibutyl phthalate is a colorless transparent oily liquid with a slight aromatic odor. It is insoluble in water, soluble in co....
- Mar 24，2020
Related Qustion
- Q:What are the effects of Dibutyl phthalate on the human body?
- A:Exposure to dibutyl phthalate (DBP) by all routes (i.e. inhalation, ingestion, dermal contact) is toxic to humans.
- May 14，2024
84-74-2(Dibutyl phthalate )Related Search:
1of4
chevron_right