ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Apoptosis >Mdm2 antagonists >Nutlin-3b

Nutlin-3b

CAS No.: 675576-97-3

Chemical Name:: Nutlin-3b

Synonyms: CS-986;Nutlin-3b;9-trioxaundecane;11-Bis(tosyloxy)-3;NUTLIN-3B;NUTLIN 3B;Nutlin-3b USP/EP/BP;(+)-NUTLIN-3;NUTLIN 3B;Nutlin-3b - Nutlin-3, (+)-;4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imid;4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one

CBNumber:: CB42624268

Molecular Formula:: C30H30Cl2N4O4

Molecular Weight:: 581.49

MOL File:: 675576-97-3.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:08

Request For Quotation

Nutlin-3b Properties

Density	1.36
storage temp.	Store at -20°C
solubility	insoluble in H2O; ≥55.5 mg/mL in EtOH; ≥57.25 mg/mL in DMSO
form	crystalline solid
pka	14.35±0.20(Predicted)
color	Off-white to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09
Signal word	Danger
Hazard statements	H302-H410-H372
Precautionary statements	P260-P264-P273-P501

Nutlin-3b Chemical Properties,Uses,Production

Description

(+)-Nutlin-3 is the enantiomer and less active form of the p53-Mdm2 protein-protein interaction inhibitor (–)-nutlin-3 . It inhibits the interaction between p53 and Mdm2 150-fold less potently than (–)-nutlin-3 with an IC₅₀ value of 13.6 μM. (+)-Nutlin-3 has been used as a negative control for the p53-modulating activity of (–)-nutlin-3 in cancer cells.

Uses

Nutlin 3b is a small molecule MDM2 antagonist.

Nutlin-3b Preparation Products And Raw materials

Raw materials

Preparation Products

Nutlin-3b Suppliers

Global( 95)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26165	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
career henan chemical co	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58

675576-97-3(Nutlin-3b)Related Search:

NUTLIN-3 N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine Imatinib mesylate Tozasertib Nutlin-3

Nutlin 3a ABT 263

chevron_left

1of2

chevron_right

Nutlin-3b 4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone 2-Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]- 4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone Nutlin 3b NUTLIN-3B;NUTLIN 3B 4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imid CS-986 4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one Nutlin-3b - Nutlin-3, (+)- (+)-NUTLIN-3;NUTLIN 3B Nutlin-3b USP/EP/BP 11-Bis(tosyloxy)-3 9-trioxaundecane 675576-97-3 677576-97-3 Inhibitors