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NUTLIN-3

NUTLIN-3 Structure
CAS No.
548472-68-0
Chemical Name:
NUTLIN-3
Synonyms
CS-390;NUTLIN-3;(?)-NUTLIN-3;Nutlin-3, >=98%;NUTLIN3;NUTLIN 3;Nutlin-3 ((±NUTLIN-3 (Free base);MDM2 Antagonist, Nutlin-3, Racemic;MDM2 Antagonist, Nutlin-3, Racemic - CAS 548472-68-0 - Calbiochem;4-(4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbony
CBNumber:
CB5101900
Molecular Formula:
C30H30Cl2N4O4
Molecular Weight:
581.49
MOL File:
548472-68-0.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

NUTLIN-3 Properties

Melting point >132oC (dec.)
Density 1.36±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 20 mg/mL, soluble
form solid
pka 14.35±0.20(Predicted)
color White
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey BDUHCSBCVGXTJM-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

NUTLIN-3 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) N6287 Nutlin-3 ≥98% (HPLC), powder 548472-68-0 1MG ₹10965.73 2022-06-14 Buy
Sigma-Aldrich(India) N6287 Nutlin-3 ≥98% (HPLC), powder 548472-68-0 5MG ₹42910.3 2022-06-14 Buy
Sigma-Aldrich(India) 444143 MDM2 Antagonist, Nutlin-3, Racemic - CAS 548472-68-0 - Calbiochem The MDM2 Antagonist, Nutlin-3, Racemic, also referenced under CAS 548472-68-0, controls the biological activity of MDM2. This small molecule/inhibitor 548472-68-0 1MG ₹15469.99 2022-06-14 Buy
Product number Packaging Price Buy
N6287 1MG ₹10965.73 Buy
N6287 5MG ₹42910.3 Buy
444143 1MG ₹15469.99 Buy

NUTLIN-3 Chemical Properties,Uses,Production

Uses

(+/-)-Nutlin-3 is a small molecule MDM2 antagonist.

Biochem/physiol Actions

Nutlin-3, an antagonist of a human homolog of murine double minute 2 (HDM2). It has the ability to inhibit the HDM2-directed degradation of p53. Nutlin-3 can also enhance the transcriptional activities of p73.

NUTLIN-3 Preparation Products And Raw materials

Raw materials

Preparation Products

NUTLIN-3 Suppliers

Global( 155)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13095 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Zhejiang J&C Biological Technology Co.,Limited 58
Henan Alfa Chemical Co., Ltd 58
Alfa Chemistry 58
LEAP CHEM CO., LTD. 58

548472-68-0(NUTLIN-3)Related Search:

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PIPERAZINE-1-CARBOXYLIC ACID DIETHYLAMIDE meso-1,2-Bis(4-chlorophenyl)ethylenediamine CHEMBRDG-BB 5543528 CHEMBRDG-BB 5570316 2,4-DIMETHOXY-BENZAMIDINE HCL
2-(4 5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOL
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(+/-)-4-[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE NUTLIN-3 2-Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-, rel- 4-[4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-, rel- 4-[4,5-Bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-Methoxy-phenyl)-4,5-dihydro-iMidazole-1-carbonyl]-piperazin-2-one Nutlin-3, >=98% NUTLIN-3 (Free base) 4-(4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbony MDM2 Antagonist, Nutlin-3, Racemic MDM2 Antagonist, Nutlin-3, Racemic - CAS 548472-68-0 - Calbiochem (?)-NUTLIN-3 Nutlin-3 ((± NUTLIN3;NUTLIN 3 CS-390 4-(cis-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one 548472-68-0 C30H30Cl2N4O4 Inhibitors