Domiphen bromide
- CAS No.
- 538-71-6
- Chemical Name:
- Domiphen bromide
- Synonyms
- DOMIPHEN;Domiphenbromide,97%;pddb;oradol;Mr C m;bradosol;bradoral;bradonit;bradasol;fungitex
- CBNumber:
- CB4271226
- Molecular Formula:
- C22H40BrNO
- Molecular Weight:
- 414.46
- MOL File:
- 538-71-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 117-119 °C (lit.) |
|---|---|
| Density | 1.1411 (rough estimate) |
| refractive index | 1.5570 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in ethanol, acetone, ethyl acetate, chloroform and water. Slightly soluble in benzene. |
| Sensitive | Hygroscopic |
| Merck | 14,3415 |
| BRN | 3922742 |
| InChIKey | OJIYIVCMRYCWSE-UHFFFAOYSA-M |
| CAS DataBase Reference | 538-71-6(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Dodecanaminium, N,N-dimethyl-N-(2-phenoxyethyl)-, bromide (1:1) (538-71-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | BQ2030000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| Hazardous Substances Data | 538-71-6(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Domiphen bromide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 247480 | Domiphen bromide 97% | 538-71-6 | 25G | ₹6137.78 | 2022-06-14 | Buy |
| ottokemi | D 2440 | Domiphen bromide | 538-71-6 | 25gm | ₹4203 | 2022-05-26 | Buy |
| ottokemi | D 2440 | Domiphen bromide | 538-71-6 | 100gm | ₹11601 | 2022-05-26 | Buy |
Domiphen bromide Chemical Properties,Uses,Production
Description
Domiphen is a quaternary ammonium compound and cationic surfactant with antimicrobial activity. It is active against A. viscosus, A. naeslundii, S. mutans, E. coli, and L. monocytogenes bacteria and inhibits C. neoformans yeast growth and spore germination. It also inhibits the human-ether-a-go-go-related gene (hERG) channel (IC50 = 1.5 μM in a whole-cell patch-clamp assay). Formulations containing domiphen have been used as antiseptics, disinfectants, and biocides in industrial, agricultural, veterinary, and clinical applications.
Uses
Domiphen bromide is employed as a phase transfer catalyst in synthetic chemistry. It is used as a quaternary ammonium cation with cationic surfactant properties. Further, it is used as an antiseptic and an active pharmaceutical ingredient.
Safety Profile
Poison by intraperitoneal and intravenous routes. hfutauon data reported. When heated to decomposiuon it emits very toxic fumes of NOx, NH3, and Br-. See also BROMIDES.