Streptomycin sulfate
- CAS No.
- 3810-74-0
- Chemical Name:
- Streptomycin sulfate
- Synonyms
- STREPTOMYCIN SULPHATE;Strepto;StreptoMycin sulfat;Streptomycin Sulphate Sterile;Estreptomicina;STREPTOMYCINI SULFAS;STREPTOMYCIN SULFATE SALT;STREPTOMYCIN SESQUISULFATE;Streptomycin Sulfate Sterile;as-15
- CBNumber:
- CB4290144
- Molecular Formula:
- C21H41N7O16S
- Molecular Weight:
- 679.65
- MOL File:
- 3810-74-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/4 15:29:52
| Melting point | >185°C (dec.) |
|---|---|
| alpha | -79～-88°(20℃/D)(c=1,H2O)(calculated on the dried basis) |
| Density | 1.2302 (rough estimate) |
| refractive index | -85 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear |
| form | powder |
| color | white to off-white |
| PH | pH (100g/l, 25℃) : 4.5～7.0 |
| Water Solubility | >=0.01 g/100 mL at 18 ºC |
| Merck | 14,8826 |
| BRN | 3894995 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | QTENRWWVYAAPBI-YZTFXSNBSA-N |
| LogP | -1.523 (est) |
| CAS DataBase Reference | 3810-74-0 |
| EPA Substance Registry System | Streptomycin sulfate (3810-74-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H361fd | |||||||||
| Precautionary statements | P201-P202-P264-P270-P301+P312-P308+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-63-42/43 | |||||||||
| Safety Statements | 26-36-36/37-45-22-60 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WK4990000 | |||||||||
| F | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29412000 | |||||||||
| NFPA 704 |
|
Streptomycin sulfate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S6501 | Streptomycin sulfate salt powder | 3810-74-0 | 5G | ₹2511.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S6501 | Streptomycin sulfate salt powder | 3810-74-0 | 25G | ₹4102.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S9137 | Streptomycin sulfate salt powder, BioReagent, suitable for cell culture | 3810-74-0 | 25G | ₹5055.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S6501 | Streptomycin sulfate salt powder | 3810-74-0 | 50G | ₹5531.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S9137 | Streptomycin sulfate salt powder, BioReagent, suitable for cell culture | 3810-74-0 | 100G | ₹12405.45 | 2022-06-14 | Buy |
Streptomycin sulfate Chemical Properties,Uses,Production
Description
Streptomycin was found in the culture broth of Streptomyces griseus by S. A. Waksman of Rutgers University in 1944; it was the second antibiotic introduced clinically (after penicillin). This drug is a water soluble, basic substance having an aminoglycoside structure and showing strong activity against a wide range of gram-positive and gram-negative bacteria including Mycobacterium. Streptomycin is the first choice among antituberculotic antibiotics and has been used for the therapy of Spirochaeta and Treponema infections.
Chemical Properties
White to off-white powder
Uses
Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor. Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis.
General Description
An antibacterial. White to light gray or pale buff powder with faint amine-like odor.
Air & Water Reactions
Hygroscopic. Water soluble.
Reactivity Profile
Streptomycin sulfate is a medicinal amino saccharide.
Health Hazard
SYMPTOMS: Symptoms of exposure to Streptomycin sulfate include skin rashes, eosinophilia, blood dyscrasias, stomatitis, anaphylactic shock, pruritus, scaling, and fever.
Fire Hazard
Flash point data for Streptomycin sulfate are not available, however Streptomycin sulfate is probably combustible.
Safety Profile
Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Human systemic effects by intraperitoneal route: flaccid paralysis without anesthesia, motor activity changes and pulmonary changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also STREPTOMYCIN and SULFATES.
Purification Methods
The sulfate is recrystallised from H2O/EtOH, washed with a little EtOH, Et2O and dried in a vacuum. [UV and IR: Grove & Randall Antibiotics Monographs 2 163 1855, Heuser et al. J Am Chem Soc 75 4013 1953, Kuehl et al. J Am Chem Soc 68 1460 1946, Regna et al. J Biol Chem 165 631 1946.] During protein synthesis it inhibits initiation and causes misreading of mRNA [Zierhut et al. Eur J Biochem 98 577 1979, Chandra & Gray Methods Enzymol 184 70 1990]. [Beilstein 18/11 V 82.]
Streptomycin sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Medi Pharma Drug House | +919930911911 | Mumbai, India | 143 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
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