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Atorvastatin lactone

Atorvastatin lactone Structure
CAS No.
125995-03-1
Chemical Name:
Atorvastatin lactone
Synonyms
5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide;PD-130694;ATORVASTATIN LACTONE;Atorvastatin USP RC H;Atorvastatin d-Lactone;Atorvastatin calcium-6;Atorvastatin Impurity H;LACTONE IMPURITY(IMP-H);(RS) Atorvastatin Lactone;Atorvastatin EP IMpurity H
CBNumber:
CB4313438
Molecular Formula:
C33H33FN2O4
Molecular Weight:
540.62
MOL File:
125995-03-1.mol
Modify Date:
2023/7/6 13:51:49

Atorvastatin lactone Properties

Melting point 103-106°C
alpha D +26.05° (c = 1 in chloroform)
Boiling point 674.8±55.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 13.39±0.40(Predicted)
color White to Light Yellow
Merck 14,864

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.99.7500
NFPA 704
0
2 0

Atorvastatin lactone price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) A3114 Atorvastatin Lactone 125995-03-1 25MG ₹5500 2022-05-26 Buy
TCI Chemicals (India) A3114 Atorvastatin Lactone 125995-03-1 100MG ₹9800 2022-05-26 Buy
Product number Packaging Price Buy
A3114 25MG ₹5500 Buy
A3114 100MG ₹9800 Buy

Atorvastatin lactone Chemical Properties,Uses,Production

Chemical Properties

Slightly Yellow Solid

Uses

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation

Atorvastatin lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Atorvastatin d-Lactone (4R,6R)-6-{2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2H-pyran-2-one (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide Atorvastatin EPIMp H (USP RCH) Atorvastatin EP IMpurity H Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide) Diepoxide Atorvastatin Lactone Diepoxide Atorvastatin Calcium Impurity D Atorvastatin Impurity H (RS) Atorvastatin Lactone ATORVASTATIN LACTONE Atorvastatin calcium-6 5-(4-fluorophenyl)-1-(2-((2R,4R) Atorvastatin Calcium Hydrate impurity H Atorvastatin EP Impurity H (Atorvastatin Lactone) 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5- Atorvastatin Lactone (Atorvastatin EP Impurity H) PD-130694 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]- 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide Atorvastatin lactone ( imp H) USP Atorvastatin Related Compound H Atorvastatin EP Impurity H/ Atorvastatin Related Compound H (Atorvastatin Lactone) Atorvastatin D5 LactoneQ: What is Atorvastatin D5 Lactone Q: What is the CAS Number of Atorvastatin D5 Lactone Q: What is the storage condition of Atorvastatin D5 Lactone Q: What are the applications of Atorvastatin D5 Lactone Atorvastatin LactoneQ: What is Atorvastatin Lactone Q: What is the CAS Number of Atorvastatin Lactone Q: What is the storage condition of Atorvastatin Lactone Q: What are the applications of Atorvastatin Lactone Atorvastatin Related Compound H (1044582)Q: What is Atorvastatin Related Compound H (1044582) Q: What is the CAS Number of Atorvastatin Related Compound H (1044582) Atorvastatin lactone (EP impurity H) (4R,6R)-6-[2-[2-(4-flfluorophenyl)-5-(1-methylethyl)-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl]-4- hydroxytetrahydro-2H-pyran-2-one Atorvastatin Impurity H(EP) Atorvastatin USP RC H Atorvastatin EP Impurity H (USP RC H)Ator. Lacton Atorvastatin impurity 9/Atorvastatin EP Impurity H/Atorvastatin Lactone/5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide AtorvastatinEPImpurityH-d5 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide Atorvastatin USP Related Compound H Atorvastatin Calcium Trihydrate EP Impurity H LACTONE IMPURITY(IMP-H) Atorvastatin Calcium Trihydrate Impurity H Atorvastatin calcium impurity H Atorvastatin EP Impurity H (Atorvastatin USP Related Compound H, Atorvastatin Lactone) 5-(4-fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-N,4-diphenyl-2-(propan-2-yl)-1H-pyrrole-3-carboxamide 125995-03-1 C33H33FN2O4 Inhibitors Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals