Benzamidine hydrochloride hydrate
- CAS No.
- 206752-36-5
- Chemical Name:
- Benzamidine hydrochloride hydrate
- Synonyms
- BENZAMIDINE HCL HYDRATE;Imino(phenyl)methylamine;BENZAMIDINIUM CHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE;[amino(phenyl)methylidene]azanium;BENZAMIDINE HYDROCHLORIDE N-HYDRATE;AMIDINOBENZENE HYDROCHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE FO;BENZAMIDINE HYDROCHLORIDE MONOHYDRATE;Benzamidine hydrochloride hydrate,98%
- CBNumber:
- CB4694173
- Molecular Formula:
- C7H11ClN2O
- Molecular Weight:
- 174.63
- MOL File:
- 206752-36-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/23 13:52:06
| Melting point | 86-88 °C(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow |
| form | Powder |
| color | White to off-white |
| PH | 5 (50g/l, H2O, 20℃) |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| BRN | 3594959 |
| CAS DataBase Reference | 206752-36-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CV6260000 | |||||||||
| F | 3-21 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2925 29 00 | |||||||||
| NFPA 704 |
|
Benzamidine hydrochloride hydrate price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B6506 | Benzamidine hydrochloride hydrate ≥99% | 206752-36-5 | 5G | ₹2901.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B6506 | Benzamidine hydrochloride hydrate ≥99% | 206752-36-5 | 25G | ₹7176.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B6506 | Benzamidine hydrochloride hydrate ≥99% | 206752-36-5 | 100G | ₹20870.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20122 | Benzamidine hydrochloride hydrate for synthesis | 206752-36-5 | 2G | ₹2720 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20122 | Benzamidine hydrochloride hydrate for synthesis | 206752-36-5 | 25G | ₹7920 | 2022-06-14 | Buy |
Benzamidine hydrochloride hydrate Chemical Properties,Uses,Production
Chemical Properties
white fine crystalline powder
Uses
Benzamidine hydrochloride hydrate is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. It is a proteolytic inhibitor and apoptosis reagent.
Application
Benzamidine hydrochloride hydrate has been used:
in western blot analysis
in immunoprecipitation
in the purification of yeast dynein
as a protease inhibitor in the preparation of brush-border membrane vesicles
for the processing of human synovial fluid, blood and eye sleep
to prevent non-specific degradation of cartilages
Biological Activity
Peptidase inhibitor.
Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases.A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.
Purification Methods
Recrystallise it from dilute HCl (crystals contain xH2O) or EtOH/few drops HCl; dry it in a vacuum. It is a proteolytic inhibitor [Jeffcoate & White J Clin Endocrinol Metab 38 155 1974, Beilstein 9 IV 898.]
Precautions
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is hygroscopic in nature.
Benzamidine hydrochloride hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21677 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 15093356674; | China | 29902 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Otto Chemie Pvt Ltd | 58 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Triveni chemicals | 58 |
| VASIN BIO LIFE SCIENCES PVT LTD | 58 |
| CHEMSWORTH | 30 |
| Henan Tianfu Chemical Co.,Ltd. | 55 |
| career henan chemical co | 58 |
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