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Amitraz

Amitraz Structure
CAS No.
33089-61-1
Chemical Name:
Amitraz
Synonyms
bipin;baam;imidamide;ZAMIR;RACET;ISOKA;MITAC;SENDER;TAKTIC;BYEBYE
CBNumber:
CB9680920
Molecular Formula:
C19H23N3
Molecular Weight:
293.41
MOL File:
33089-61-1.mol
MSDS File:
SDS
Modify Date:
2024/5/31 8:52:38
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Amitraz Properties

Melting point 86-87°C
Boiling point 425.25°C (rough estimate)
Density 1.1280
vapor pressure 3.4×10-4 Pa (25 °C)
refractive index 1.5892 (estimate)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.33 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
pka 4.2 (weak base)
Water Solubility 0.08 mg l-1
form Powder/Solid
color White
λmax 247nm(lit.)
Merck 14,486
InChIKey QXAITBQSYVNQDR-ZIOPAAQOSA-N
CAS DataBase Reference 33089-61-1(CAS DataBase Reference)
NIST Chemistry Reference Amitraz(33089-61-1)
EPA Substance Registry System Amitraz (33089-61-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H317-H373-H410
Precautionary statements  P260-P273-P280-P301+P312-P302+P352-P314
Hazard Codes  Xn;N,N,Xn
Risk Statements  22-43-48/22-50/53
Safety Statements  22-24-36/37-60-61
RIDADR  UN 3077
WGK Germany  3
RTECS  ZF0480000
HazardClass  9
PackingGroup  III
HS Code  29252900
Toxicity LD50 in male rats, female mice, rabbits, guinea pigs, bobwhite quail (mg/kg): 800, >1600, >100, >400, 788 orally; LD50 in rabbits, male rats (mg/kg): >200, >1600 dermally; LC50 (48 hr) in rainbow trout, Japanese carp: 3.3, 1.2 ppm (Labonne)
NFPA 704
0
2 0

Amitraz price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 45323 Amitraz PESTANAL?, analytical standard 33089-61-1 250MG ₹7555.85 2022-06-14 Buy
TCI Chemicals (India) A2608 Amitraz min. 97.0 % 33089-61-1 250MG ₹3900 2022-05-26 Buy
TCI Chemicals (India) A2608 Amitraz min. 97.0 % 33089-61-1 1G ₹6900 2022-05-26 Buy
Product number Packaging Price Buy
45323 250MG ₹7555.85 Buy
A2608 250MG ₹3900 Buy
A2608 1G ₹6900 Buy

Amitraz Chemical Properties,Uses,Production

Chemical Properties

Amitraz forms colorless needle-like crystals. Liquid formulations may contain flammable organic solvents.

Uses

Amitraz is an antiparasitic used to control red spider mites, leaf miners and scale insects. This compound is active by inhibiting the targets monoaminooxidase enzyme.

Definition

ChEBI: A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5.

General Description

White monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Unstable in acid.

Agricultural Uses

Insecticde, Acaricide, Veterinary medicine: Registered for control of pear psylla on pears, whitefly and mites on pears and cotton; cattle, dogs, sheep, and hog dip to control ticks, mange mites, lice and other pests. Not permitted on apples. Used to control red spider mites, leaf miners, scale insects, and aphids. Also used on cotton to control bollworms, white fly, leaf worms, and tobacco budworms. Not registered for use in EU countries

Trade name

AAZDIENO®; ACARAC®; ACADREX®; ARMY®; AZODIENO®; BAAM®; BOOTS BTS 27419®; BTS 27,419®; BUMETRAN®; COYOTE®; DANICUT®; ECTODEX®; EDRIZAN®; EDRIZAR®; GARIAL®; ISTAMBUL®; MITABAN®; MITAC®; OVASYN®; OVIDREX®; PARSEC®; ROTRAZ®; SENDER®; TAC-PLUS®; TACTIK®; TRIATIX®; TRIATOX®; TUDY®; VAPCOZIN TAKTIC®; UPJOHN U-36059®

Pharmacology

The mechanism of action of amitraz has not been completely elucidated, and, presently, a dual mode of action appearsmost likely. Firstly, the enzymemonoamine oxidase, which metabolizes neurotransmitter amines in mites and ticks, is inhibited. Secondly, octopamine receptors in the central nervous system of ectoparasites are activated by amitraz, thereby modifying tonic muscle contractions. The effect of amitraz is to induce increased neuronal activity, abnormal behavior, detachment, and death of mites and ticks.

Potential Exposure

Those engaged in the manufacture, formulation and application of this insecticide and acaricide. A rebuttable presumption against registration for amitraz was issued on April 6, 1977 by United States Environmental Protection Agency on the basis of oncogenicity. Incompatibilities: Keep away from strong oxidizers and strong acids. Acids may render this material unstable.

Metabolic pathway

14C-Amitraz is applied on lemons grown under glasshouse conditions at final harvest and the applied radioactivity is quantitatively recovered, predominantly in the peel (86%). The total residue at harvest contains amitraz, N-methyl-N'-(2,4-xylyl)formamidine, and formyl-2',4'-xylydine and conjugates of 4-amino- m-toluic acid and the conjugated metabolites which are convertible to 2,4-xylidine. Amitraz is readily hydrolyzed at low pH values, forming acid-stable formyl-2,4-xylydine which can be further hydrolyzed to 2,4-xylidine.

Metabolism

Amitraz is poorly absorbed when applied topically to animals. By contrast, orally administered amitraz is rapidly and extensively absorbed. The metabolism and excretion of amitraz are also rapid. It is hydrolyzed to N-(2,4-dimethylphenyl)-N -methyl formamidine and 2,4- dimethyl formamidine and the final product, 4-amino-3- methylbenzoic acid, is converted to non-toxic conjugates. The latter are excreted in the urine and, to a lesser extent, in bile.

Shipping

UN2763 Triazine pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Those engaged in the manufacture, formulation and application of this insecticide and acaricide. A rebuttable presumption against registration for amitraz was issued on April 6, 1977 by United States Environmental Protection Agency on the basis of oncogenicity. Incompatibilities: Keep away from strong oxidizers and strong acids. Acids may render this material unstable.

Waste Disposal

In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

Amitraz Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid Triethyl orthoformate Cyclohexane Urethane Methylamine
m-Xylene Water Tosyl chloride N-2,4-DIMETHYLPHENYL-N'-METHYLFORMAMIDINE 2,4-Dimethyl aniline
Benzonitrile N-Methylformamide 2,4-Dimethylaniline hydrochloride Sodium hydroxide
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Preparation Products

AMITRAZ METABOLITE HYDROCHLORIDE Hexazinone

Amitraz Suppliers

Global( 454)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
NGL Fine Chem limited +91-8866366396 +91-8866366396 Mumbai, India 26 58 Inquiry
Manasvi Life Sciences +91-9391326151 +91-9490072008 Hyderabad, India 39 58 Inquiry
Diligent Life Care +91-2262515000 +91-9898023247 Gujarat, India 12 58 Inquiry
Modern Insecticides Limited 91-161-5043900 Punjab, India 23 58 Inquiry
SRIRAMCHEM Laboratories Pvt., Ltd. 91-9686622202 Karnataka, India 21 58 Inquiry
NGL Fine-chem Ltd 91-22-26636450 Maharashtra, India 7 58 Inquiry
Global Chem Asia Pacific 91-9849161572 Hyderabad, India 255 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Supplier Advantage
NGL Fine Chem limited 58
Manasvi Life Sciences 58
Diligent Life Care 58
Modern Insecticides Limited 58
SRIRAMCHEM Laboratories Pvt., Ltd. 58
NGL Fine-chem Ltd 58
Global Chem Asia Pacific 58
CLEARSYNTH LABS LTD. 58
TCI Chemicals (India) Pvt. Ltd. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58

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Amitraz Spectrum

Amitraz(33089-61-1)MSAmitraz(33089-61-1)1HNMRAmitraz(33089-61-1)13CNMRAmitraz(33089-61-1)IR1Amitraz(33089-61-1)IR2

33089-61-1(Amitraz)Related Search:

N,N-Dimethylacetamide Methylparaben Poly(dimethylsiloxane) Kresoxim-methyl Thiophanate-methyl
Chlorodimethylphenylsilane N,N'-Methylenebisacrylamide ALMITRINE N,N-Dimethylaniline N,N-Dimethyl-1,4-phenylenediamine
METSULFURON METHYL Bensulfuron methyl Methyl acrylate Methyl acetate Acetamiprid
Dimethyl sulfone N,N-Dimethylformamide Dimethyl sulfoxide
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n’-(2,4-dimethylphenyl)-n-(((2,4-dimethylphenyl)imino)methyl)-n-methylmethan N’-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl-imino]methyl]-N-methylmethanimidamide,N-Methylbis(2,4-xylyliminoethyl)amine n-methyl-bis(2,4-xylyliminomethyl)amine r.d.27419 TAKTIC SENDER RACET U-36059 ZAMIR amitraze amitrazestrella azadieno azaform bootsbts27419 ectodex fumilata methanimidamide,n’-(2,4-dimethylphenyl)-n-(((2,4-dimethylphenyl)imino)methyl mitaban n,n’-((methylimino)dimethylidyne)di-2,4-xylidine n,n’-(methyliminodimethylidyne)bis-4-xylidine n,n-bis(2,4-xylyliminomethyl)methylamine N,N-di-(2,4-Xylyliminomethyl)methylamine 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-diene BTS 27419 BAAM(R) AURORA KA-686 ISOKA BYEBYE ENT 27967 EDRIZAR methyl-bis(2,4-xylyliminomethyl)amine AMITAC AMITRAZ Triatox Triazid AMITRAZ, 250MG, NEAT AMITRAZ PESTANAL (N-METHYLBIS- (2,4-XYLY BATE CYPERMETHRINE + DIMETHOATE, AMITRAZ Methanimidamide, N-(2,4-dimethylphenyl)-N-(2,4-dimethylphenyl)iminomethyl-N-methyl- amitraz (bsi,iso,ansi,ban,jmaf) amitraz (ISO) N,N-bis(2,4-xylyliminomethyl) methylamine MONOAMITRAZ 2-methyl-1,3-di(2,4-xylylimino)-2-azapropane acarac upjohnu-36059 MITAC MITAC(R) PARSEC N'-N'-[(METHYLIMINO)-DIMETHYLIDINE]-BIS-(2,4-XYLIDINE) N-METHYL-N'-2,4-XYLYL-N-(N-2,4-XYLYLFORMIMIDOYL)-FORMAMIDINE N,N'-(Methyliminodimethyl(idyne))bis-2,4-xylidine 1,5-BIS(2,4-DIMETHYLPHENYL)-3-METHYL-1,3,5-TRIAZAPENTA-1,4-DIENE N'-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)iminomethyl]-N-methyl-formamidine Amitraz 250mg [33089-61-1] N'-(2,4-DIMETHYLPHENYL)-N-[[(2,4-DIMETHYLPHENYL)IMINO]METHYL]-N-METHYLMETHANIMIDAMIDE AMITRAZTECHNICAL AMigard Apivar ND