5-(TETRADECYLOXY)-2-FUROIC ACID
- CAS No.
- 54857-86-2
- Chemical Name:
- 5-(TETRADECYLOXY)-2-FUROIC ACID
- Synonyms
- TOFA;mdl14514;RMI-14514;TOFA (RMI14514;RMI14514; MDL14514;TOFA (RMI14514:MDL14514);5-tetradecyloxy-2-furonicacid;5-(TETRADECYLOXY)-2-FUROIC ACID;5-(TETRADECYLOXY)-2-FUROIC TOFA;TOFA - CAS 54857-86-2 - Calbiochem
- CBNumber:
- CB4759746
- Molecular Formula:
- C19H32O4
- Molecular Weight:
- 324.45
- MOL File:
- 54857-86-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/7/12 16:55:01
| Melting point | 112-115 °C |
|---|---|
| Boiling point | 441.7±25.0 °C(Predicted) |
| Density | 1.003±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: 2.5 mg/mL |
| form | solid |
| pka | 3.55±0.10(Predicted) |
| color | white to beige |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
5-(TETRADECYLOXY)-2-FUROIC ACID price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T6575 | TOFA ≥98% (HPLC) | 54857-86-2 | 5MG | ₹19840 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T6575 | TOFA ≥98% (HPLC) | 54857-86-2 | 25MG | ₹79340 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 613450 | TOFA - CAS 54857-86-2 - Calbiochem A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme invol | 54857-86-2 | 5MG | ₹39430 | 2022-06-14 | Buy |
5-(TETRADECYLOXY)-2-FUROIC ACID Chemical Properties,Uses,Production
Uses
TOFA has been used as a lipid biosynthesis inhibitor in mesenchymal stromal cells (MSCs), human pluripotent stem cells., an acetyl-CoA carboxylase 1 inhibitor in murine adipocyte cell lines., a lipolysis inhibitor in cancer stem cells (CSCs).
Definition
ChEBI: A member of the class of furans that is 2-furoic acid in which the hydrogen at position 5 is replaced by a tetradecyloxy group.
Biochem/physiol Actions
5-(Tetradecyloxy)-2-furoic acid (TOFA) elicits hypolipidemic?functionality by favoring fatty acid breakdown and at the same time preventing biosynthesis. It induces apoptosis in pancreatic cancer cells and favors tumor suppression.
5-(TETRADECYLOXY)-2-FUROIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 85)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10259 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |
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TOFA
5-(tetradecyloxy)-2-furancarboxylicaci
5-tetradecyloxy-2-furonicacid
mdl14514
RMI-14514
TOFA (5-(Tetradecyloxy)-2-furoic acid)
5-(TETRADECYLOXY)-2-FURANCARBOXYLIC ACID
5-(TETRADECYLOXY)-2-FUROIC ACID
2-Furancarboxylic acid,5-(tetradecyloxy)-
TOFA (RMI14514
TOFA (RMI14514:MDL14514)
5-(TETRADECYLOXY)-2-FUROIC TOFA
TOFA - CAS 54857-86-2 - Calbiochem
RMI14514; MDL14514
inhibit,RMI 14514,Acetyl-CoA Carboxylase,ACC, Acetyl Coenzyme A Carboxylase,RMI-14514,TOFA,MDL 14514,MDL-14514,Inhibitor
54857-86-2
A to C
Biochemicals and Reagents
BioChemical
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
Enzymes, Inhibitors, and Substrates
Acetyl CoA-Carboxylase