5-(TETRADECYLOXY)-2-FUROIC ACID
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- ₹19840 - ₹79340
- Product name: 5-(TETRADECYLOXY)-2-FUROIC ACID
- CAS: 54857-86-2
- MF: C19H32O4
- MW: 324.45
- EINECS:
- MDL Number:MFCD01726059
- Synonyms:TOFA;5-(tetradecyloxy)-2-furancarboxylicaci ;5-tetradecyloxy-2-furonicacid ;mdl14514 ;RMI-14514;TOFA (5-(Tetradecyloxy)-2-furoic acid);5-(TETRADECYLOXY)-2-FURANCARBOXYLIC ACID;5-(TETRADECYLOXY)-2-FUROIC ACID
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberT6575
- Product descriptionTOFA ≥98% (HPLC)
- Packaging5MG
- Price₹19840
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number613450
- Product descriptionTOFA - CAS 54857-86-2 - Calbiochem A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme invol
- Packaging5MG
- Price₹39430
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT6575
- Product descriptionTOFA ≥98% (HPLC)
- Packaging25MG
- Price₹79340
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T6575 | TOFA ≥98% (HPLC) | 5MG | ₹19840 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 613450 | TOFA - CAS 54857-86-2 - Calbiochem A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme invol | 5MG | ₹39430 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T6575 | TOFA ≥98% (HPLC) | 25MG | ₹79340 | 2022-06-14 | Buy |
Properties
Melting point :112-115 °C
Boiling point :441.7±25.0 °C(Predicted)
Density :1.003±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 2.5 mg/mL
form :solid
pka :3.55±0.10(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Boiling point :441.7±25.0 °C(Predicted)
Density :1.003±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 2.5 mg/mL
form :solid
pka :3.55±0.10(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
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Description
TOFA (5-(Tetradecyloxy)-2-furoic acid) is a cell-permeable small molecule, functional as an inhibitor of fatty acid synthesis through inhibition of acetyl-CoA carboxylase (ACC). Inhibition of this enzyme reduces the availability of endogenous fatty acids for generation of phosphatidylcholine, the major phospholipid in cell membranes. Blockage of ACC also depletes malonyl-CoA levels, indicated to serve a proapoptotic role in cell regulation, and reduction of malonyl-CoA related to TOFA inhibition is reported to confer survival to cancer cells treated with a cytotoxin. TOFA is also described to stimulate citrate accumulation in the cell, which leads to a suppression of glycolysis by citrate-induced inhibition of phosphofructokinase.More related product prices
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