phenindamine tartrate

phenindamine tartrate Structure
CAS No.
569-59-5
Chemical Name:
phenindamine tartrate
Synonyms
Nolahist;Pernovine;phenindamine tartrate
CBNumber:
CB4899853
Molecular Formula:
C19H19N.C4H6O6
Molecular Weight:
411.452
MOL File:
569-59-5.mol
Modify Date:
2023/4/23 13:52:06

phenindamine tartrate Properties

Melting point 160°
solubility Sparingly soluble in water; slightly soluble in ethanol (96%); practically insoluble in ether .

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice (mg/kg): 27 i.v., 170 i.p., 265 orally (Schallek)

phenindamine tartrate Chemical Properties,Uses,Production

Chemical Properties

A white or almost white, voluminous powder.

Uses

Histamine H1 receptor antagonist; antihistamine.

General Description

Phenindamine tartrate,2,3,4,9-tetrahydro-2-methyl-9-phenyl-1H-indeno[2, 1-c]pyridine bitartrate, occurs as a creamy-white powder, usuallywith a faint odor and sparingly soluble in water (1:40). A 2%aqueous solution has a pH of about 3.5. It is most stable inthe pH range of 3.5 to 5.0 and is unstable in solutions of pH 7or higher. Oxidizing substances or heat may cause isomerizationto an inactive form.
Structurally, phenindamine can be regarded as an unsaturatedpropylamine derivative, in that the rigid ring systemcontains a distorted, trans-alkene. Like the other commonlyused antihistamines, it may produce drowsiness and sleepiness;it may also cause a mildly stimulating action in somepatients and insomnia when taken just before bedtime.

phenindamine tartrate Preparation Products And Raw materials

Raw materials

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Preparation Products

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TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9968 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
phenindamine tartrate Pernovine Nolahist 569-59-5 C19H19NC4H6O6