Sodium fusidate
- CAS No.
- 751-94-0
- Chemical Name:
- Sodium fusidate
- Synonyms
- Fusidic;FUCIDIN;Fusidate;fusin;fusidin;fucidine;(3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID;zn6;ZN 6-Na;sq16360
- CBNumber:
- CB5216967
- Molecular Formula:
- C31H49NaO6
- Molecular Weight:
- 540.72
- MOL File:
- 751-94-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | >200°C (dec.) |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | H2O: soluble |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water |
| Sensitive | Moisture & Light Sensitive |
| Merck | 13,4339 |
| CAS DataBase Reference | 751-94-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV5775000 | |||||||||
| HS Code | 29419000 | |||||||||
| Toxicity | LD50 in mice (g/kg): 0.2 i.v. (Godtfredsen, Nature 1962) | |||||||||
| NFPA 704 |
|
Sodium fusidate price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | F0881 | Fusidic acid sodium salt ≥98% (TLC) | 751-94-0 | 1G | ₹24605.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | F0881 | Fusidic acid sodium salt ≥98% (TLC) | 751-94-0 | 5G | ₹103216.38 | 2022-06-14 | Buy |
| SRL | 36511 | Sodium Fucidate (Na-FC), 97.5% | 751-94-0 | 1Gms | ₹3000 | 2022-05-26 | Buy |
| SRL | 36511 | Sodium Fucidate (Na-FC), 97.5% | 751-94-0 | 5Gms | ₹8000 | 2022-05-26 | Buy |
Sodium fusidate Chemical Properties,Uses,Production
Description
Fusidic acid is a fusidane antibiotic originally isolated from F. coccineum. It is active against the Gram-positive bacteria S. aureus, S. pyogenes, C. diphtheriae, B. subtilis, and C. tetani (MIC50s = 0.01-20 μg/ml) but not the Gram-negative bacteria E. coli, S. typhimurium, and P. vulgaris or the fungi C. albicans and A. fumigatus (MIC50s = >100 μg/ml for all). Fusidic acid inhibits ribosomal recycling and protein translocation, processes mediated by elongation factor G (EF-G), in isolated E. coli ribosomes (IC50s = ~0.1 and ~200 μM, respectively). Topical administration of fusidic acid (2%) reduces the number of skin colony forming units (CFUs) and levels of TNF-α and IL-6 in a mouse model of methicillin-resistant S. aureus (MRSA) skin wound infection.
Chemical Properties
White or almost white, crystalline powder, slightly hygroscopic.
Uses
Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steriodal metabolite of Fusidum coccineum which is a potent Gram positive antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid also suppresses NO lysis of pancreatic islet cells.
General Description
Fusidic acid is an antibiotic substance, resembling the structure of a steroid. It belongs to the class of fusidanes.
Sodium fusidate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Vyshno Bio Sciences | 91-7095439993 | Hyderabad, India | 239 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| Anand Agencies | 58 |
| Pharma Affiliates | 58 |
| Vyshno Bio Sciences | 58 |
| CHEMSWORTH | 30 |
| Maas Pharma Chemicals | 58 |
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