PI 828

CAS No.: 942289-87-4

Chemical Name:: PI 828

Synonyms: PI 828;PI 828,PI828;LY 294002, 4′-NH2;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-

CBNumber:: CB52455753

Molecular Formula:: C19H18N2O3

Molecular Weight:: 322.36

MOL File:: 942289-87-4.mol

Modify Date:: 2024/7/2 8:55:11

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PI 828 Properties

Boiling point	534.2±50.0 °C(Predicted)
Density	1.316±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
pka	4.14±0.10(Predicted)
form	Off-white solid
color	White to yellow

PI 828 price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	440206	LY 294002, 4ʹ-NH₂ - CAS 942289-87-4 - Calbiochem A cell-permeable LY 294002 4′-amino derivative with enhanced potency against p110α/β/δ/γ.	942289-87-4	5MG	₹15469.99	2022-06-14	Buy

Product number	Packaging	Price	Buy
440206	5MG	₹15469.99	Buy

PI 828 Chemical Properties,Uses,Production

General Description

A cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC₅₀ in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.

Biological Activity

PI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.

PI 828 Preparation Products And Raw materials

Raw materials

Preparation Products

PI 828 Suppliers

Global( 38)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	China	4694	58	Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	17316404525	China	9649	58	Inquiry
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	China	4552	58	Inquiry
Wuhan Jingkangen Biomedical Technology Co., Ltd	13720134139 13720134139	China	5371	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48467	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9282	58	Inquiry
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	China	9887	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	58
Nantong QuanYi Biotechnology Co., Ltd	58
Wuhan Jingkangen Biomedical Technology Co., Ltd	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
RD International Technology Co., Limited	58
Shanghai Chaolan Chemical Technology Center	58

PI 828 Spectrum

PI 828(942289-87-4)¹HNMR

942289-87-4(PI 828)Related Search:

Phenyl carbamate 2-(Dimethylamino)-8-phenyl-4H-1-benzopyran-4-one LY 294002 HYDROCHLORIDE PI 828 4H-1-Benzopyran-4-one, 2-(diethylamino)-

2-(Diethylamino)-8-phenyl-4H-1-benzopyran-4-one 2-(Etilmetilammino)-8-fenilcromone [Italian]

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PI 828 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one 8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one 8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem LY 294002, 4′-NH2 PI 828,PI828 4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)- 942289-87-4