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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >HCV Protease Inhibitors >VX-222

VX-222

VX-222 Structure
CAS No.
1026785-59-0
Chemical Name:
VX-222
Synonyms
VCH222;VX-222;CS-481;VCH-222;VCH 222;cis-Lomibuvir;VX-222, VCH222;VX222(Lomibuvir);Lomibuvir (VX-222;VX-222 (VCH-222, LoMibuvir)
CBNumber:
CB52501168
Molecular Formula:
C25H35NO4S
Molecular Weight:
445.61
MOL File:
1026785-59-0.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:58
Request For Quotation

VX-222 Properties

Boiling point 640.5±55.0 °C(Predicted)
Density 1.21
storage temp. Store at -20°C
solubility ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH
form solid
pka 3.67±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

VX-222 Chemical Properties,Uses,Production

Description

Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).

Uses

VX-222, s a novel, potent and selective inhibitor of HCV polymerase .

VX-222 Preparation Products And Raw materials

Raw materials

Preparation Products

VX-222 Suppliers

Global( 79)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49403 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29820 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40067 58 Inquiry
Supplier Advantage
Capot Chemical Co.,Ltd. 60
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
InvivoChem 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
LEAPCHEM CO., LTD. 58
Shanghai Acmec Biochemical Technology Co., Ltd. 58
Aladdin Scientific 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 58

VX-222 Spectrum

VX-222(1026785-59-0)1HNMR

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VX-222 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid VCH 222 VCH222 VCH-222 VX-222, VCH222 VX-222 (VCH-222, LoMibuvir) 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]- Lomibuvir (VX-222, VCH-222) VCH222; VX 222; VCH 222; VCH-222;VX-222 VX222(Lomibuvir) CS-481 Lomibuvir (VX-222 cis-Lomibuvir 1026785-59-0 Inhibitors Inhibitor