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HS-173

HS-173 Structure
CAS No.
1276110-06-5
Chemical Name:
HS-173
Synonyms
HS-173;CS-1007;HS 173;HS173;HS-173 USP/EP/BP;PI3K Inhibitor HS-173 HS173;HS-173, 98%, a novel PI3K inhibitor;PI3K,Apoptosis,Phosphoinositide 3-kinase,HS-173,Inhibitor,inhibit;ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate;6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester
CBNumber:
CB52708130
Molecular Formula:
C21H18N4O4S
Molecular Weight:
422.46
MOL File:
1276110-06-5.mol
Modify Date:
2023/6/8 9:03:09
Request For Quotation

HS-173 Properties

Melting point >193°C (dec.)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly)
pka 6.84±0.40(Predicted)
form Solid
color Grey to Brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

HS-173 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 5.32384 PI3K Inhibitor, HS-173 - Calbiochem PI3 K alpha inhibitor; anti-fibrolytic agent; HS-173 1276110-06-5 10MG ₹16470 2022-06-14 Buy
Product number Packaging Price Buy
5.32384 10MG ₹16470 Buy

HS-173 Chemical Properties,Uses,Production

Description

HS-173 is an imidazopyridine analog that acts as a PI3Kα inhibitor with an IC50 value of 0.8 nM. It demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 μM, respectively. HS-173 is reported to induce apoptosis by arresting the cell cycle at the G2/M phase and by activating caspases. It has also been shown to block VEGF-induced angiogenesis both in vitro and in vivo.

Uses

HS-173 is a potent PI3Kα inhibitor with anticancer activity.

HS-173 Preparation Products And Raw materials

Raw materials

Preparation Products

HS-173 Suppliers

Global( 96)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 12962 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
Zhengzhou Alfa Chemical Co.,Ltd 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58

HS-173 Spectrum

HS-173(1276110-06-5)1HNMR

1276110-06-5(HS-173)Related Search:

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ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester HS-173 HS-173 6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester HS 173;HS173 CS-1007 HS-173, 98%, a novel PI3K inhibitor Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester HS-173 USP/EP/BP PI3K Inhibitor HS-173 HS173 PI3K,Apoptosis,Phosphoinositide 3-kinase,HS-173,Inhibitor,inhibit 1276110-06-5 Inhibitors