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Methyl 4-methoxyacetoacetate

Methyl 4-methoxyacetoacetate Structure
CAS No.
41051-15-4
Chemical Name:
Methyl 4-methoxyacetoacetate
Synonyms
4-Methoxyacetoacetate;Methyl 4-methoxy-3-oxobu;Methyl methoxyacetoacetate;Methyl 4-Methoxyacetoacetat;Dolutegravir Intermediates2;METHYL 4-METHOXYACETOACETATE;Methyl 3-oxo-4-methoxybutyrate;METHYL 4-METHOXYACETOXYACETATE;methyl 4-methoxy-3-oxobutyrate;Methyl4-Methoxyacetoacetate>
CBNumber:
CB5291234
Molecular Formula:
C6H10O4
Molecular Weight:
146.14
MOL File:
41051-15-4.mol
MSDS File:
SDS
Modify Date:
2024/7/29 17:07:33

Methyl 4-methoxyacetoacetate Properties

Melting point -80℃
Boiling point 89 °C/8.5 mmHg (lit.)
Density 1.129 g/mL at 25 °C (lit.)
refractive index n20/D 1.431(lit.)
Flash point 193 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
pka 9.88±0.46(Predicted)
Specific Gravity 1.129
color Colorless to Light yellow to Light orange
BRN 1761215
InChIKey QGBPKJFJAVDUNC-UHFFFAOYSA-N
LogP 0.340 (est)
CAS DataBase Reference 41051-15-4(CAS DataBase Reference)
NIST Chemistry Reference Methyl 4-methoxyacetoacetate(41051-15-4)
EPA Substance Registry System Methyl 4-methoxyacetoacetate (41051-15-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10
HS Code  29189900
NFPA 704
2
0 0

Methyl 4-methoxyacetoacetate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 281506 Methyl 4-methoxyacetoacetate 97% 41051-15-4 5G ₹6150 2022-06-14 Buy
Sigma-Aldrich(India) 281506 Methyl 4-methoxyacetoacetate 97% 41051-15-4 25G ₹18260 2022-06-14 Buy
TCI Chemicals (India) M1031 Methyl 4-Methoxyacetoacetate min. 97.0 % 41051-15-4 5G ₹3900 2022-05-26 Buy
TCI Chemicals (India) M1031 Methyl 4-Methoxyacetoacetate min. 97.0 % 41051-15-4 25G ₹10000 2022-05-26 Buy
Product number Packaging Price Buy
281506 5G ₹6150 Buy
281506 25G ₹18260 Buy
M1031 5G ₹3900 Buy
M1031 25G ₹10000 Buy

Methyl 4-methoxyacetoacetate Chemical Properties,Uses,Production

Chemical Properties

colorless to yellow liquid

Uses

Methyl 4-Methoxyacetoacetate is a reactant in the formation of an abiotic poorphyrinogen in aqueous solution.

Preparation

The preparation method of a 4-methoxyl group methyl acetoacetate: add solvents tetrahydrofurane in a kettle. and pass into rare gas element, the temperature in the kettle arranging reactor is 15-25℃, industrial sodium hydride and metal alkaline compound is added under whipped state, add solvents tetrahydrofurane again, the mixed solution reaction 4-6h of methyl alcohol and 4-chloro methyl acetoacetate is dripped in less than 20℃, then be warming up to 20-25℃ and continue reaction 4-15h, TLC detection reaction is complete, reduce system temperature to 6-10℃, add the hydrochloric acid soln regulation system pH=5-7 that volumetric molar concentration is 2mol/L, stratification, after separatory, upper strata is concentrated is spin-dried for removing solvents tetrahydrofurane, then colorless product 4-methoxyl group methyl acetoacetate is obtained by wiped film molecular distillation.

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