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Chloropyramine

Chloropyramine Structure
CAS No.
59-32-5
Chemical Name:
Chloropyramine
Synonyms
Allergan;Synpen;Avapena;Synopen;synopenr;allergans;Suprastin;Synopen R;Allergan S;Anaphylline
CBNumber:
CB5327911
Molecular Formula:
C16H20ClN3
Molecular Weight:
289.8
MOL File:
59-32-5.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

Chloropyramine Properties

Melting point 25°C
Boiling point bp0.2 154-155°
Density 1.1031 (rough estimate)
refractive index 1.6010 (estimate)
pka 9.00±0.28(Predicted)
NIST Chemistry Reference Chloropyramine(59-32-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

Chloropyramine Chemical Properties,Uses,Production

Uses

Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.

Synthesis

Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.

Synthesis_59-32-5

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1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-pyridin 2-((p-Chlorobenzyl)(2-(dimethylamino)ethyl)amino)pyridine Allergan S n-(p-chlorobenzyl)-n',n'-dimethyl-n-(2-pyridyl)ethylenediamine CHLOROPYRAMINE BASE CHLOROPYRAMINE 2-[(4-chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine allergans Anaphylline Avapena Chlorneoantergan Chloroneoantergan Chloropyribenzamine Chlorpyramine Ethylenediamine, N-(p-chlorobenzyl)-N',N'-dimethyl-N-(2-pyridyl)- Halopyramine n-((4-chlorophenyl)methyl)-n’,n’-dimethyl-n-2-pyridinyl-2-ethanediamine n-(p-chlorobenzyl)-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediamin p-Chlorbenzyl-alpha-pyridyl-dimethyl-aethylendiamin Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)- Suprastin Synopen Synopen R synopenr Synpen Chloropyramine USP/EP/BP 1,2-Ethanediamine, N1-[(4-chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl- N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine Allergan FAK inhibitor C4 59-32-5 69-32-5 C16H20ClN3