ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Alanine derivatives >Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine

CAS No.: 607366-20-1

Chemical Name:: Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine

Synonyms: FMOC-DAP(IVDDE)-OH;FMOC-DPR(IVDDE)-OH;FMOC-L-DAP(IVDDE)-OH;N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine;3-[1-(4,4-DiMethyl-2,6-dioxocyclohexylidene)-3-MethylbutylaMino]-FMoc-L-alanine, 95%;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine USP/EP/BP;FMoc-Nβ-(4,4-diMethyl-2,6-dioxocyclohex-1-ylidene)-3-Methylbutyl-L-2,3-diaMinopropionic acid;Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid;Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid

CBNumber:: CB5413560

Molecular Formula:: C31H36N2O6

Molecular Weight:: 532.63

MOL File:: 607366-20-1.mol

Modify Date:: 2022/12/30 16:20:48

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Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Properties

Boiling point	733.7±60.0 °C(Predicted)
Density	1.221
storage temp.	Store at -15°C to -25°C.
pka	3.47±0.10(Predicted)

SAFETY

Risk and Safety Statements

HS Code

2924297099

NFPA 704

	1
0		0

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	8.52083	Fmoc-Dpr(ivDde)-OH Novabiochem?	607366-20-1	1G	₹8240	2022-06-14	Buy
Sigma-Aldrich(India)	8.52083	Fmoc-Dpr(ivDde)-OH Novabiochem?	607366-20-1	5G	₹38080	2022-06-14	Buy
Sigma-Aldrich(India)	8.52083	Fmoc-Dpr(ivDde)-OH Novabiochem?	607366-20-1	8520830025	₹244170	2022-06-14	Buy

Product number	Packaging	Price	Buy
8.52083	1G	₹8240	Buy
8.52083	5G	₹38080	Buy
8.52083	8520830025	₹244170	Buy

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Chemical Properties,Uses,Production

Uses

N-alpha-Fmoc-N-beta-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic Acid is used in the synthesis of phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors. It is also used to prepare peptidomimetic ligands for α4β1 integrin on Jurkat T-leukemia cells.

General Description

This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3].

When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4].

The product number for this product was previously 04-12-1195.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Suppliers

Global( 79)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	China	888	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26216	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
VladaChem GmbH	+49-7246-3082843	Germany	1860	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	China	39009	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Alpha Biopharmaceuticals Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
Dideu Industries Group Limited	58
BOC Sciences	58
Nextpeptide Inc	58
VladaChem GmbH	58
LEAPCHEM CO., LTD.	58
Suzhou ARTK Medchem Co., Ltd.	58

607366-20-1(Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine)Related Search:

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ETHANE EC 2.6.1.2 4-Methoxyphenylacetic acid N,N-Dimethylformamide Dimethyl carbonate

Fmoc-8-amino-3,6-dioxaoctanoic acid Dimethyl sulfate Dimethyl sulfoxide

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N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-(1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL)-L-2,3-DIAMINOPROPIONIC ACID N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-BETA-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL]-L-2,3-DIAMINOPROPIONIC ACID N-ALPHA-FMOC-N-BETA-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-DIAMINOPROPIONIC ACID 3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine FMOC-N-BETA-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-2,3-DIAMINOPROPIONIC ACID FMOC-DPR(IVDDE)-OH FMOC-DAP(IVDDE)-OH FMOC-L-DAP(IVDDE)-OH (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)propanoic acid N2-Fmoc-N3-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid FMoc-Nβ-(4,4-diMethyl-2,6-dioxocyclohex-1-ylidene)-3-Methylbutyl-L-2,3-diaMinopropionic acid Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine 3-[1-(4,4-DiMethyl-2,6-dioxocyclohexylidene)-3-MethylbutylaMino]-FMoc-L-alanine, 95% Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid (2S)-3-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid L-Alanine, 3-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine USP/EP/BP Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1 607366-20-1 amino acid amino acids