ChemicalBook > Product Catalog >API >Synthetic Anti-infective Drugs >Antiviral drugs >Arbidol hydrochloride
Arbidol hydrochloride
- CAS No.
- 131707-23-8
- Chemical Name:
- Arbidol hydrochloride
- Synonyms
- Abidol;Doxetine;ARBIDOL HCL;Abiduoer.HCI;Arbidole HCl;Umifenovir HCl;yansuanabiduoer;Soluble Arbidol;Arbidol hydrochlorid;ARBIDOL HYDROCHLORIDE
- CBNumber:
- CB5438596
- Molecular Formula:
- C22H26BrClN2O3S
- Molecular Weight:
- 513.88
- MOL File:
- 131707-23-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | 133-137?C |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO: soluble20mg/mL protein, clear |
| form | powder |
| color | white to beige |
| Stability | Hygroscopic |
| InChI | InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H |
| InChIKey | OMZHXQXQJGCSKN-UHFFFAOYSA-N |
| SMILES | C(C1=C(N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12)CSC1C=CC=CC=1)(=O)OCC.Cl |
| CAS DataBase Reference | 131707-23-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| Toxicity | guinea pig,LD50,oral,> 3gm/kg (3000mg/kg),Drugs of the Future. Vol. 17, Pg. 1079, 1992. | |||||||||
| NFPA 704 |
|
Arbidol hydrochloride price More Price(2)
Arbidol hydrochloride Chemical Properties,Uses,Production
Description
Umifenovir is a broad-spectrum antiviral agent. It inhibits the replication of H5N1 influenza (IC50 = 30 μg/ml) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro (IC50 = 3.537 μM). Umifenovir inhibits entry of hepatitis C virus (HCV) pseudoparticles in Huh7 cells (IC50 = 6 μg/ml) and inhibits Zika virus protein synthesis in Vero cells. In vivo, umifenovir (45 mg/kg) reduces the formation of influenza-induced lung lesions in ferrets.
Chemical Properties
Off White to Pale Yellow Solid
Uses
Arbidol hydrochloride (ARB) is a small monocular compound. It is used to prevent severe pneumonia and virus-associated cytokine dysregulation induced by influenza viruses (IFV). ARB also possesses some immunomodulatory properties, including the effects of interferon induction and macrophage activation.
Arbidol is a broad-spectrum antiviral that has demonstrated activity against a number of enveloped and non-enveloped viruses, and is used clinically to treat influenza. Arbidol inhibits viral entry into host cell and stimulates immune response. Arbidol inhibits fusion between the viral capsid and the cell membrane of the target cell, thus preventing viral entry.
Arbidol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 432)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Apicore Pharmaceuticals Pvt Ltd | +91-2662267177 +91-2662267166 | Gujarat, India | 181 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | China | 2996 | 58 | Inquiry |
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | China | 225 | 58 | Inquiry |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | CHINA | 9427 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
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1H-INDOLE-3-CARBOXYLIC ACID, 6-BROMO-4-[(DIMETHYLAMINO)METHYL]-5-HYDROXY-1-METHYL-2-[(PHENYLTHIO)METHYL]-, ETHYL ESTER, MONOHYDROCHLORIDE
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yansuanabiduoer
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Arbidol hydrochlorid
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C22H25BrN2O3SHClH2O
C22H25BrN2O3SHCl
C22H26BrClN2O3S
C22H25BrN2O3SClH
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131707-23-8