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LOSARTAN-D4

LOSARTAN-D4 Structure
CAS No.
1030937-27-9
Chemical Name:
LOSARTAN-D4
Synonyms
MK-954-d4;Cozaar-d4;DuP-753 D4;LOSARTAN-D4;[2H4]-Losartan;Reaxys ID: 18951469;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol;2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]-1H-imidazole-5-methanol;Losartan D4Q: What is Losartan D4 Q: What is the CAS Number of Losartan D4 Q: What is the storage condition of Losartan D4 Q: What are the applications of Losartan D4
CBNumber:
CB5465064
Molecular Formula:
C22H19ClD4N6O
Molecular Weight:
426.94
MOL File:
Mol file
Modify Date:
2023/5/18 11:31:10

LOSARTAN-D4 Properties

Melting point 184-190?C
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly),Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

LOSARTAN-D4 Chemical Properties,Uses,Production

Description

Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM. 

Chemical Properties

White Solid

Uses

As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive.

LOSARTAN-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 63)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SIMSON PHARMA LIMITED +91-8291074273 Shanghai, India 228 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56057 58 Inquiry
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 02584622273; China 3022 58 Inquiry
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol Cozaar-d4 MK-954-d4 LOSARTAN-D4 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]-1H-imidazole-5-methanol Reaxys ID: 18951469 [2H4]-Losartan DuP-753 D4 Losartan D4Q: What is Losartan D4 Q: What is the CAS Number of Losartan D4 Q: What is the storage condition of Losartan D4 Q: What are the applications of Losartan D4 1030937-27-9 C22H19ClD4N6O C22H19D4ClN6O Heterocycles Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals