ChemicalBook > Product Catalog >API >Circulatory system drugs >Antihypertensive drugs >Losartan carboxylic acid

Losartan carboxylic acid

CAS No.: 124750-92-1

Chemical Name:: Losartan carboxylic acid

Synonyms: exp3174;Losartan Carboxylic Acid;e-3174;LOSARTAN CARBOXY ACID;EXP 317;l-158641;AKOS 91941;ALSTint-A07;Losartan acid;E-3174, EXP-3174

CBNumber:: CB4399601

Molecular Formula:: C22H21ClN6O2

Molecular Weight:: 436.89

MOL File:: 124750-92-1.mol

MSDS File:: SDS

Modify Date:: 2025/1/27 9:38:02

Request For Quotation

Losartan carboxylic acid Properties

Melting point	130-132°C
Boiling point	707.8±70.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Dimethylformamide, Dimethyl Sulfoxide, Methanol
form	Solid
pka	0.79±0.50(Predicted)
color	Light-Yellow
InChIKey	ZEUXAIYYDDCIRX-UHFFFAOYSA-N
SMILES	C1(CCCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C(C(O)=O)=C(Cl)N=1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H317-H360D-H362
Precautionary statements	P202-P260-P263-P280-P302+P352-P308+P313
Safety Statements	24/25
HS Code	29339900

Losartan carboxylic acid price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SMB01354	Losartan carboxylic acid ≥95% (HPLC)	124750-92-1	5MG	₹6556.66	2022-06-14	Buy
Sigma-Aldrich(India)	SMB01354	Losartan carboxylic acid ≥95% (HPLC)	124750-92-1	25MG	₹26236.34	2022-06-14	Buy

Product number	Packaging	Price	Buy
SMB01354	5MG	₹6556.66	Buy
SMB01354	25MG	₹26236.34	Buy

Losartan carboxylic acid Chemical Properties,Uses,Production

Description

Losartan carboxylic acid is a physiologically active metabolite of losartan , produced by cytochrome P450 isoforms in the liver. Like the parent compound, losartan carboxylic acid is a potent AT₁ antagonist (K_is = 0.57 and 0.67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of action than losartan. However, the metabolite has very low oral bioavailability. Losartan, but not its metabolite, inhibits platelet aggregation in vitro.

Chemical Properties

Light-Yellow Solid

Definition

ChEBI: A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid.

Losartan carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Losartan Allisartan Isoproxil N-Trityl Losartan Carboxylic Acid

Losartan carboxylic acid Suppliers

Global( 175)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Allmpus Laboratories Pvt Ltd	+91-9518738415 +91-9167862134	Maharashtra, India	657	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6514	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	7859	58	Inquiry
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	China	9642	58	Inquiry
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	CHINA	9414	58	Inquiry

Supplier	Advantage
Allmpus Laboratories Pvt Ltd	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Finetech Industry Limited	58
Baoji Guokang Healthchem co.,ltd	58

124750-92-1(Losartan carboxylic acid)Related Search:

Losartan potassium Ethyl acetate Metoprolol Candesartan cilexetil Valsartan

Irbesartan Losartan Trityl losartan 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]-methyl-1H-imidazole-5-carboxylic acid (LOSARTAN METABOLITE). AKOS 91707

AKOS 91711 Losartan carboxylic acid

chevron_left

1of3

chevron_right

AKOS 91941 2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID ’-biphenyl)-4-yl)methyl)- 1h-imidazole-5-carboxylicacid,2-butyl-4-chloro-1-((2’-(14-tetrazol-5-yl)(1,1 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid 1H-Imidazole-5-carboxylicacid, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 2-Butyl-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicAcid EXP 317 Losartan Carboxylic AcidDiscontinued see product # L470510 l-158641 EXP 3174 (LOSARTAN CARBOXYLIC ACID) 2-Butyl-3-[[2'-(2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-5-chloro-3H-imidazole-4-carboxylic acid 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylic acid 2-Butyl-4-chloro-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]imidazole-5-carboxylic acid 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)- Losartan Carboxylic Acid NEW CATALOGUE NUMBER: see product # L470510 Losartan acid Losartan carboxylic acid, >=98% 2-Butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-formic acid LOSARTAN,2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID Losartan Impurity 14 1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1 E-3174;EXP-3174;E 3174;EXP 3174;E3174;EXP3174;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1;1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-CARBOXYLIC ACID Losartan Carboxylic Acid USP/EP/BP 2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID USP/EP/BP Losartan Carboxylic Acid (Losartan Carboxylate) Losartan Carboxylic acid Impurity Losartan carboxylic acidQ: What is Losartan carboxylic acid Q: What is the CAS Number of Losartan carboxylic acid Q: What is the storage condition of Losartan carboxylic acid Q: What are the applications of Losartan carboxylic acid 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid ALSTint-A07 2-n-butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid E-3174, EXP-3174 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid E-3174;EXP-3174;E 3174;EXP 3174;E3174;EXP3174 LOSARTAN CARBOXY ACID Losartan Carboxylic Acid e-3174 exp3174 Losartan carboxylic acid in methanol 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Aci Losartan Carboxylic Acid, 10 mM in DMSO Alisartan cilexetil impurity I 124750-92-1 C22H21ClN6O2 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Heterocycles