Oxamic acid
- CAS No.
- 471-47-6
- Chemical Name:
- Oxamic acid
- Synonyms
- Oxamate;2-aMino-2-oxoacetic acid;Oxalamic acid;Oxamic acid Oxalic acid monoamide;OXAMIC ACID;OXAMIDIC ACID;OxamicAcid>Oxamicacid,98%;Glycine, 2-oxo-;Oxamic acid 98%
- CBNumber:
- CB5667743
- Molecular Formula:
- C2H3NO3
- Molecular Weight:
- 89.05
- MOL File:
- 471-47-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/18 10:52:13
| Melting point | 207-210 °C (dec.) (lit.) |
|---|---|
| Boiling point | 165.08°C (rough estimate) |
| Density | 1.6193 (rough estimate) |
| refractive index | 1.4264 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Crystalline Powder |
| pka | 1.60±0.20(Predicted) |
| color | White |
| Water Solubility | Soluble in water 108 mg/mL. |
| Merck | 14,6917 |
| BRN | 1743294 |
| InChI | InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6) |
| InChIKey | SOWBFZRMHSNYGE-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(N)=O |
| CAS DataBase Reference | 471-47-6(CAS DataBase Reference) |
| EPA Substance Registry System | Oxamic acid (471-47-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29241990 | |||||||||
| NFPA 704 |
|
Oxamic acid price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | O3750 | Oxamic acid ≥98% | 471-47-6 | 25G | ₹14884.38 | 2022-06-14 | Buy |
| ALFA India | ALF-B20344-22 | Oxamic acid, 98% | 471-47-6 | 100g | ₹32071 | 2022-05-26 | Buy |
| ALFA India | ALF-B20344-14 | Oxamic acid, 98% | 471-47-6 | 25g | ₹6600 | 2022-05-26 | Buy |
| ALFA India | ALF-B20344-06 | Oxamic acid, 98% | 471-47-6 | 5g | ₹2277 | 2022-05-26 | Buy |
| TCI Chemicals (India) | O0084 | Oxamic Acid | 471-47-6 | 5G | ₹2100 | 2022-05-26 | Buy |
Oxamic acid Chemical Properties,Uses,Production
Description
Oxamic acids also known to as oxalic acid monoamides have emerged as potent precursors for the generation of the carbamoyl radical. Oxamic acids can easily undergo decarboxylation through a single electron oxidation resulting in the generation of the reactive carbamoyl radical, which can then engage in diverse radical reactions or undergo a second single electron oxidation as originally unveiled by Minisci. Oxamic acids are thus versatile intermediates for the synthesis of nitrogen-containing organic molecules[1]. The oxidative decarboxylation of oxamic acids can be mediated through thermal, photochemical, electrochemical or photoelectrochemical means, generating carbamoyl radicals, which may further add to unsaturated systems to provide a broad range of important amides. Oxidative decarboxylation of oxamic acids also offers a straightforward entry for the preparation of urethanes, ureas, and thioureas.
Chemical Properties
Oxamic acid is a white, water-soluble solid. It is the monoamide ofoxalic acid. It can react with metal carbonates to form oxamate. Oxamic acid inhibits lactate dehydrogenase A.
Uses
Oxamic acid is an ozone oxidation product and is used in the synthesis of hydroxybenzimidazoles preparation as potential anti tumor agents targeting human lactate dehydrogenase A.This compound is suitable for lactate dehydrogenase (LDH) related research.
Definition
ChEBI: Oxamic acid is a dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia. It has a role as an Escherichia coli metabolite. It is a conjugate acid of an oxamate.
Application
Oxamic acid (OA) has applications in polymer chemistry. It increases the water solubility of certain polymers, including polyester,epoxide, and acrylic upon binding with them. Oxamic acid can be used as a reactant to prepare 6-phenanthridinecarboxamide by direct C-H carbamoylation reaction using ammonium persulfate in DMSO. It can also be used as an organic ligand to prepare functionalized metal oxide nanoparticles for various biological applications. OA along with p-aminobenzoic acid is used to functionalize Au nanoparticles for the development of a sensor to detect Fe3+ ions by the calorimetric method.
References
[1] Ikechukwu Martin Ogbu . “Oxamic acids: useful precursors of carbamoyl radicals.” Chemical Communications 58 55 (2022): Pages 7593-7607.
Oxamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Sense Chemicals (Shanghai) Co., Ltd. | +86-21-52751036; +8613818977689 | China | 224 | 58 | Inquiry |
| Hongxiong | +undefined18915499068 | China | 120 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13127 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
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