ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >3-IODO-L-TYROSINE

3-IODO-L-TYROSINE

CAS No.: 70-78-0

Chemical Name:: 3-IODO-L-TYROSINE

Synonyms: H-Tyr;NSC210787;3-I-L-Tyr-OH;H-3-I-TYR-OH;Iodotyrosine;H-TYR(M-I)-OH;H-TYR(3-I)-OH;3-Iodo-Tyr-OH;3-IODO-TYROSINE;H-L-TYR(3-I)-OH

CBNumber:: CB5721061

Molecular Formula:: C9H10INO3

Molecular Weight:: 307.09

MOL File:: 70-78-0.mol

MSDS File:: SDS

Modify Date:: 2023/5/10 18:56:37

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3-IODO-L-TYROSINE Properties

Melting point	210 °C (dec.)(lit.)
Density	1.7280 (estimate)
storage temp.	-20°C
solubility	dilute aqueous acid: soluble
form	Solid
Boiling point	391.0±42.0 °C(Predicted)
pka	2.21±0.20(Predicted)
color	White to off-white
Sensitive	Light Sensitive
Merck	14,5047
BRN	2941266
Stability	Hygroscopic
InChIKey	UQTZMGFTRHFAAM-ZETCQYMHSA-N
CAS DataBase Reference	70-78-0(CAS DataBase Reference)
EPA Substance Registry System	L-Tyrosine, 3-iodo- (70-78-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P305+P351+P338-P310

Safety Statements

24/25

WGK Germany

8-10-23

HS Code

29225090

NFPA 704

	0
1		0

3-IODO-L-TYROSINE price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	I8250	3-Iodo-L-tyrosine	70-78-0	1G	₹5823.85	2022-06-14	Buy
Sigma-Aldrich(India)	I8250	3-Iodo-L-tyrosine	70-78-0	5G	₹21390.2	2022-06-14	Buy
Sigma-Aldrich(India)	I8250	3-Iodo-L-tyrosine	70-78-0	25G	₹72278.53	2022-06-14	Buy
TCI Chemicals (India)	I0075	3-Iodo-L-tyrosine	70-78-0	1G	₹3400	2022-05-26	Buy
TCI Chemicals (India)	I0075	3-Iodo-L-tyrosine	70-78-0	5G	₹9600	2022-05-26	Buy

Product number	Packaging	Price	Buy
I8250	1G	₹5823.85	Buy
I8250	5G	₹21390.2	Buy
I8250	25G	₹72278.53	Buy
I0075	1G	₹3400	Buy
I0075	5G	₹9600	Buy

3-IODO-L-TYROSINE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

3-iodo-l-tyrosine is used in the inhibition of tyrosine hydroxylase. 3-iodo-L-tyrosine is used in the rapid induction of prolactin secretion.

Definition

ChEBI: The monoiodotyrosine that is L-tyrosine carrying an iodo-substituent at position C-3 of the benzyl group.

General Description

Iodotyrosine coupled with di-iodotyrosine results in the synthesis of 3,5,3′-tri-iodothyronine (T3) or 3,3′,5′-tri-iodothyronine (rT3).

Purification Methods

Likely impurities are tyrosine, diiodotyrosine and iodide. Crystallise it by dissolving it in concentrated ammonia (~200mg in ~20mL), evaporate to ~5mL and NH4Cl is added to pH4.5—5.0. After a few hours at 0o, the amino acid crystallises in needles. It is filtered off, washed with a little ice-cold H2O and dried in a vacuum. Alternatively dissolve it in dilute ammonia at room temperature, then add dilute acetic acid to pH 6. Store it at 0o. Recrystallisation of ~250mg from H2O (~5mL) removes any diiodotyrosine. It is an inhibitor of tyrosine hydroxylase with a Ki of ~500nM. [Harrington & Rivers Biochem J 38 320 1944, Rivers Chem & Ind (London) 21 1956, Beilstein 14 III 1562, 14 IV 1562.]

3-IODO-L-TYROSINE Preparation Products And Raw materials

Raw materials

3,5-Diiodo-L-tyrosine dihydrate L-Tyrosine

Preparation Products

3-IODO-L-TYROSINE Suppliers

Global( 242)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Ria International India Private Limited	08048372349Ext 317	Mumbai, India	7	58	Inquiry
Suzhou Ryan Pharmachem Technology Co.,Ltd.	+86-512-68780025 +8618962125825	China	137	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	16914	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29894	58	Inquiry
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	China	2931	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CHEMSWORTH	30
CLEARSYNTH LABS LTD.	58
TCI Chemicals (India) Pvt. Ltd.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Ria International India Private Limited	58
Suzhou Ryan Pharmachem Technology Co.,Ltd.	58
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58

3-IODO-L-TYROSINE Spectrum

3-IODO-L-TYROSINE(70-78-0)MS 3-IODO-L-TYROSINE(70-78-0)¹HNMR 3-IODO-L-TYROSINE(70-78-0)IR1 3-IODO-L-TYROSINE(70-78-0)IR2 3-IODO-L-TYROSINE(70-78-0)Raman

70-78-0(3-IODO-L-TYROSINE)Related Search:

REVERSE T3 3,5-Diiodo-L-thyronine 3,3',5-Triiodo-L-thyronine 3,3',5-TRIIODOTHYROPROPIONIC ACID Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED

3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID N-ForMyl Thyroxine 3,5,3',5'-Tetraiodo Thyroaldehyde 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetaMide

3,5,3',5'-Tetraiodo Thyrolactic Acid 3,3',5-TRIIODOTHYROACETIC ACID O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Liothyronine IMpurity E Levothyroxine impurity E

Sodium levothyroxine Levothyroxine sodium N-Acetyl-3,5-diiodo-L-tyrosine

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3-Iodo-4-hydroxyphenylalanine 4-Hydroxy-3-iodophenylalanine (S)-2-AMino-3-(4-hydroxy-3-iodophenyl)propanoic acid L-TYROSINE, 3-IODO- 3-I-L-Tyr-OH 3-Iodo-L-tyrosine≥ 98% (HPLC) H-L-Phe(3-I,4-OH)-OH 3-IODO-TYROSINE 3-IODO-L-TYROSINE 3-MONOIODO-L-TYROSINE S(-)-3-IODO-4-HYDROXY-PHENYLAMINE M-IODO-L-TYROSINE 3-iodine-L- tyrosine H-TYR(M-I)-OH H-TYR(3-I)-OH H-L-TYR(3-I)-OH H-3-IODO-TYR-OH H-3-I-PHE(4-OH)-OH H-3-I-TYR-OH 3-Monoiodo-L-tyrosine 3-Iodo-L-tyrosine Iodotyrosine (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid 3-IODO-L -TYROSINE 97% 3-Iodo-L-tyrosine,97% 3-Iodo-Tyr-OH 3-Iodo-L-tyrosine,3-Monoiodo-L-tyrosine 3-Iodo-L-tyrosine, 97% 1GR (2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate 3-Iodo-L-tyrosine> 3-1odo-L-tyrosine 3-IODO-L-TYROSINE USP/EP/BP Liothyronine Impurity 1 MIT (amino acid) NSC210787 Tyrosine,3-iodo-, L- (8CI) Liothyronine Impurity 2 Metoprolol Impurity 35 H-Tyr 70-78-0 IC6H34OHCH2CHNH2CO2H C9H10INO3 Tyrosine Derivatives Unnatural Amino Acid Derivatives Peptide Synthesis Specialty Synthesis amino Unusual Amino Acids Amino Acids 13C, 2H, 15N Amino Acids Biochemistry Biological-modified Amino Acids Amino Acids & Derivatives Inhibitors Aromatics Chiral Reagents